aconitate hydratase
An iron-containing enzyme catalyzing the dehydration of citric acid to cis-aconitic acid, a reaction of significance in the tricarboxylic acid cycle. SYN: aconitase.

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acon·i·tate hy·dra·tase (ə-konґĭ-tāt hiґdrə-tās) [EC 4.2.1.3] an enzyme of the lyase class that catalyzes the interconversion of citrate and isocitrate, a reaction of the tricarboxylic acid cycle (q.v.). The enzyme, a nonheme iron protein, is named for the cis-aconitate formed as an intermediate in the dehydration and rehydration reaction. Called also aconitase.

Medical dictionary. 2011.

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  • Aconitase — Aconitate hydratase Structure de l aconitase (PDB 1ACO) …   Wikipédia en Français

  • List of EC numbers (EC 4) — This list contains a list of EC numbers for the fourth group, EC 4, lyases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 4.1: Carbon Carbon LyasesEC… …   Wikipedia

  • aconitase — SYN: aconitate hydratase. * * * acon·i·tase ə kän ə .tās n an enzyme occurring in many animal and plant tissues that accelerates the conversion of citric acid first into aconitic acid and then into isocitric acid * * * acon·i·tase (ə… …   Medical dictionary

  • MÉTABOLISME — Rien ne se crée, rien ne se perd. Le principe de conservation de l’énergie et de la matière ne souffre aucune exception. Aussi les êtres vivants ne sont ils que des transformateurs d’énergie: ils reçoivent du dehors de l’énergie chimique et ils… …   Encyclopédie Universelle

  • Aconitase — protein Name = aconitase 1, soluble caption = width = HGNCid = 117 Symbol = ACO1 AltSymbols = IREB1 EntrezGene = 48 OMIM = 100880 RefSeq = NM 002197 UniProt = P21399 PDB = ECnumber = 4.2.1.3 Chromosome = 9 Arm = p Band = 21.1… …   Wikipedia

  • aconitase — noun Aconitate hydratase, an enzyme that catalyses the stereospecific isomerization of citrate to isocitrate via cis aconitate in the tricarboxylic acid cycle …   Wiktionary

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