Biliary atresia
Congenital absence or closure of the major bile ducts, the ducts that drain bile from the liver. Biliary atresia results in a progressive inflammatory process which may lead to cirrhosis of the liver. The infant looks normal at birth but develops jaundice after the age of 2 to 3 weeks with yellowing of the eyes and skin, light-colored stools and dark urine caused by the build up of the pigment called bilirubin in the blood. The abdomen may be swollen with a firm, enlarged liver. Weight loss and irritability develop as the jaundice increases. There is one case of biliary atresia out of every 15,000 live births. Females are affected slightly more often than males. The preferred treatment is to attach the small intestine directly to the liver at the spot where bile is found or expected to drain. Bile flow is re-established in approximately 80% of infants who are operated before 3 months of age. Of these, about 50% will have some bile drainage and as many as 30% will have complete bile drainage. About 20% of infants will not be helped by the procedure. In these cases, the only option is a liver transplant.

* * *

biliary atresia n absence or underdevelopment of the bile ducts and esp. the extrahepatic bile ducts

* * *

a congenital or acquired condition in which the bile ducts do not drain. Babies usually present within the first few weeks of life with jaundice that does not improve with time. Some forms of biliary atresia can be corrected surgically, but if diagnosis has been delayed the condition may lead to irreversible liver damage.

* * *

obliteration or hypoplasia of one or more components of the bile ducts due to arrested fetal development, resulting in persistent jaundice and liver damage ranging from biliary stasis to biliary cirrhosis. As portal hypertension progresses, infants develop splenomegaly.

Medical dictionary. 2011.

Look at other dictionaries:

  • Biliary atresia — Infobox Disease Name = PAGENAME Caption = Operative view of complete extrahepatic biliary atresia. DiseasesDB = 1400 ICD10 = ICD10|Q|44|2|q|38 ICD9 = ICD9|751.61 ICDO = OMIM = 210500 MedlinePlus = eMedicineSubj = ped eMedicineTopic = 237 MeshName …   Wikipedia

  • biliary atresia — a congenital or acquired condition in which the bile ducts do not drain. Babies usually present within the first few weeks of life with jaundice that does not improve with time. Some forms of biliary atresia can be corrected surgically, but if… …   The new mediacal dictionary

  • biliary atresia splenic malformation syndrome — a rare congenital condition of biliary atresia together with polysplenia or some other anomaly of the spleen. It may be associated with other anomalies, including defects of the portal vein, heart, lungs, and liver. Called also BASM s …   Medical dictionary

  • Atresia — is a condition in which a body orifice or passage in the body is abnormally closed or absent. Examples of atresia include:* Anorectal atresia malformation of the opening between the rectum and anus. * Aural atresia (see Microtia) a congenital… …   Wikipedia

  • Atresia — Absence of a normal opening or failure of a structure to be tubular. Atresia can affect many structures in the body, including: {{}}Anal atresia congenital absence of a hole at the bottom end of the intestine. Also called imperforate anus. Aortic …   Medical dictionary

  • Atresia, biliary — Congenital absence or closure of the major bile ducts, the ducts that drain bile from the liver. Biliary atresia results in a progressive inflammatory process which may lead to cirrhosis of the liver. The infant looks normal at birth but develops …   Medical dictionary

  • Biliary — Having to do with the gallbladder, bile ducts, or bile. The biliary system itself consists of the gallbladder and bile ducts and, of course, the bile. For example, biliary atresia is the absence or closure of the major bile ducts, the ducts that… …   Medical dictionary

  • atresia — n. 1) congenital absence or abnormal narrowing of a body opening. See: biliary atresia, duodenal atresia, tricuspid atresia 2) the degenerative process that affects the majority of ovarian follicles. Usually only one Graafian follicle will… …   The new mediacal dictionary

  • Esophageal atresia — Classification and external resources Common anatomical types of esophageal atresia a) Esophageal atresia with distal tracheoesophageal fistula (86%). b) Isolated esophageal atresia without tracheoesophageal fistula (7%). c) H type… …   Wikipedia

  • Intestinal atresia — Classification and external resources ICD 10 Q41, Q42 ICD 9 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”