immunological tolerance

immunological tolerance
a failure of the body to distinguish between materials that are 'self', and therefore to be tolerated, and those that are 'not self', against which it mounts an immune response. Tolerance results from the interaction of antigens with lymphocytes under conditions in which the lymphocytes are not activated but rendered unresponsive.

Medical dictionary. 2011.

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  • immunological tolerance — Tolerance Tol er*ance, n. [L. tolerantia: cf. F. tol[ e]rance.] 1. The power or capacity of enduring; the act of enduring; endurance. [1913 Webster] Diogenes, one frosty morning, came into the market place, shaking, to show his tolerance. Bacon.… …   The Collaborative International Dictionary of English

  • immunological tolerance — immunological tolerance. См. иммунологическая толерантность. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • immunological tolerance — noun The failure of the body to recognize antigens with consequent absence of antibody production • • • Main Entry: ↑immune …   Useful english dictionary

  • immunological tolerance — Specific unresponsiveness to antigen. Self tolerance is a process occurring normally early in life due to suppression of self reactive lymphocyte clones. Tolerance to foreign antigens can be induced in adult life by exposure to antigens under… …   Dictionary of molecular biology

  • immunological tolerance — a failure of the body to distinguish between materials that are ‘self’, and therefore to be tolerated, and those that are ‘not self’, against which it mounts an immune response. Tolerance results from the interaction of antigens with lymphocytes… …   The new mediacal dictionary

  • Tolerance — Tol er*ance, n. [L. tolerantia: cf. F. tol[ e]rance.] 1. The power or capacity of enduring; the act of enduring; endurance. [1913 Webster] Diogenes, one frosty morning, came into the market place, shaking, to show his tolerance. Bacon. [1913… …   The Collaborative International Dictionary of English

  • Tolerance of the mint — Tolerance Tol er*ance, n. [L. tolerantia: cf. F. tol[ e]rance.] 1. The power or capacity of enduring; the act of enduring; endurance. [1913 Webster] Diogenes, one frosty morning, came into the market place, shaking, to show his tolerance. Bacon.… …   The Collaborative International Dictionary of English

  • tolerance — 1. The ability to endure or be less responsive to a stimulus, especially over a period of continued exposure. 2. The power of resisting the action of a poison or of taking a drug continuously or in large doses without injurious effects. [L.… …   Medical dictionary

  • tolerance — n. the reduction or loss of the normal response to a drug or other substance that usually provokes a reaction in the body. Drug tolerance may develop after taking a particular drug over a long period of time. In such cases increased doses are… …   The new mediacal dictionary

  • immunological memory — The systems responsible for the situation where reactions to a second or subsequent exposure to an antigen are more extensive than those seen on first exposure (but see also immunological tolerance. The memory is best explained by clonal… …   Dictionary of molecular biology

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