acyl-CoA

acyl-CoA
Condensation product of a carboxylic acid and coenzyme A; metabolic intermediate of importance, notably in the oxidation and synthesis of fat. SYN: acyl-coenzyme A.
- acyl-CoA dehydrogenase (NADPH) enzyme catalyzing the reversible reduction of enoyl-CoA derivatives of chain length 4–16, with NADPH as the hydrogen donor, forming acyl-CoA and NADP+. SYN: enoyl-CoA reductase.
- acyl-CoA synthetase 1. general term for enzymes (EC 6.2.1.x) that form acyl-CoA, now called ligases; 2. specifically, long-chain fatty acid –CoA ligase.

Medical dictionary. 2011.

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  • Acyl-CoA — is a coenzyme involved in the metabolism of fatty acids. It is a temporary compound formed when coenzyme A (CoA) attaches to the end of a long chain fatty acid, inside living cells. The CoA is then removed from the chain, carrying two carbons… …   Wikipedia

  • Acyl-CoA — Strukturmodell des Coenzym A. Strukturformel von Coenzym A. Coenzym A (auch Koenzym A, kurz CoA oder CoASH) ist ein Coenzym, das zur „Aktivierung“ von Alkansäuren und deren …   Deutsch Wikipedia

  • Acyl CoA dehydrogenase — is the enzyme used to catalyze the first step of β oxidation in Fatty acid metabolism. ReactionThe following reaction is the oxidation of the fatty acid by FAD.The enzyme catalyzes the formation of a double bond between the C 2 and C 3. The end… …   Wikipedia

  • acyl-CoA desaturase — acyl CoA de·sat·ur·ase (aґsəl ko aґ de sachґə rās) stearoyl CoA 9 desaturase …   Medical dictionary

  • Acyl-CoA hydrolase — In enzymology, an acyl CoA hydrolase (EC number|3.1.2.20) is an enzyme that catalyzes the chemical reaction:acyl CoA + H2O ightleftharpoons CoA + a carboxylateThus, the two substrates of this enzyme are acyl CoA and H2O, whereas its two products… …   Wikipedia

  • Acyl-CoA dehydrogenase (NADP+) — In enzymology, an acyl CoA dehydrogenase (NADP+) (EC number|1.3.1.8) is an enzyme that catalyzes the chemical reaction:acyl CoA + NADP+ ightleftharpoons 2,3 dehydroacyl CoA + NADPH + H+Thus, the two substrates of this enzyme are acyl CoA and… …   Wikipedia

  • Acyl-CoA oxidase — In enzymology, an acyl CoA oxidase (EC number|1.3.3.6) is an enzyme that catalyzes the chemical reaction:acyl CoA + O2 ightleftharpoons trans 2,3 dehydroacyl CoA + H2O2Thus, the two substrates of this enzyme are acyl CoA and O2, whereas its two… …   Wikipedia

  • acyl CoA — ac·yl CoA (aґsəl ko aґ) acyl coenzyme A …   Medical dictionary

  • acyl CoA synthetase — ac·yl CoA syn·the·tase (aґsəl ko aґ sinґthə tās) 1. any enzyme of the ligase class that catalyzes the formation of an activated acyl coenzyme A thioester; individual enzymes are specific for a range of fatty acid chain lengths. See …   Medical dictionary

  • acyl-CoA dehydrogenase — ac·yl CoA de·hy·dro·gen·ase (aґsəl ko aґ de hiґdro jən ās) [EC 1.3.99.3] any of several enzymes of the oxidoreductase class that catalyze the oxidation of acyl coenzyme A thioesters to the enoyl coenzyme A form, using a flavin… …   Medical dictionary

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