Biological response modifiers (BRMs)
: Substances that stimulate the body's response to infection and disease. The body naturally produces small amounts of these substances. Scientists can produce some of them in the laboratory in large amounts for use in treating cancer, rheumatoid arthritis, and other diseases. BMRs used in biological therapy include monoclonal antibodies, interferon, interleukin-2 (IL-2), and several types of colony- stimulating factors (CSF, GM-CSF, G-CSF). Interleukin-2 and interferon are BRMs being tested for the treatment of advanced malignant melanoma. Interferon is a BRM now in use to treat hepatitis C. The side effects of BRM therapy often include flu-like symptoms such as chills, fever, muscle aches, weakness, loss of appetite, nausea, vomiting, and diarrhea. Some patients develop a rash, and some bleed or bruise easily. Interleukin therapy can cause swelling. Depending on the severity of these problems, patients may need to stay in the hospital during treatment. These side effects are usually short-term and go gradually away after treatment stops.

Medical dictionary. 2011.

Look at other dictionaries:

  • Biological response modifiers — Biological response modifers, also known as BRM s, are substances that the human body produces naturally, as well as something that scientists can create in a lab. These substances arouse the body s response to an infection. Some of these are… …   Wikipedia

  • BMRs (biological response modifiers) — Substances that stimulate the body s response to infection and disease. The body naturally produces small amounts of these substances. Scientists can produce some of them in the laboratory in large amounts for use in treating cancer, rheumatoid… …   Medical dictionary

  • Modifiers, biological response (BRMs) — Substances that stimulate the body s response to infection and disease. The body naturally produces small amounts of these substances. Scientists can produce some of them in the laboratory in large amounts for use in treating cancer, rheumatoid… …   Medical dictionary

  • Biological therapy — Treatment to stimulate or restore the ability of the immune (defense) system to fight infection and disease. Biological therapy is thus any form of treatment that uses the body s natural abilities that constitute the immune system to fight… …   Medical dictionary

  • Therapy, biological — Treatment to stimulate or restore the ability of the immune (defense) system to fight infection and disease. Biological therapy is thus any form of treatment that uses the body s natural abilities that constitute the immune system to fight… …   Medical dictionary

  • Immunotherapy — Treatment to stimulate or restore the ability of the immune (defense) system to fight infection and disease. Biological therapy is thus any form of treatment that uses the body s natural abilities that constitute the immune system to fight… …   Medical dictionary

  • Biotherapy — Treatment to stimulate or restore the ability of the immune (defense) system to fight infection and disease. Biological therapy is thus any form of treatment that uses the body s natural abilities that constitute the immune system to fight… …   Medical dictionary

  • Neuvenge — Neuvenge, Lapuleucel T (APC 8024), is a therapeutic cancer vaccine (TCV) in development (clinical trial) by Dendreon (DNDN). It uses the immunotherapy platform approach first successfully demonstrated on the U.S. Food and Drug Administration… …   Wikipedia

  • List of AIDS-related topics — This is a list of AIDS related topics, many of which were originally taken from the public domain U.S. Department of Health Glossary of HIV/AIDS Related Terms, 4th Edition. [http://www.aidsinfo.nih.gov/ed resources/glossary/] NOTOC A AACTG… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”