adenosine
1. A condensation product of adenine and d-ribose; a nucleoside found among the hydrolysis products of all nucleic acid s and of the various adenine nucleotides. A. accumulates in severe combined immunodeficiency disease. 2. A potent coronary vasodilator used in place of exercise for radionuclide myocardial perfusion studies. SYN: 9-β-d-ribofuranosyladenine.
- a. cyclic phosphate a. 3′,5′-cyclic monophosphate.
- a. deaminase an enzyme found in mammalian tissues, capable of catalyzing the deamination of a., forming inosine and ammonia. A deficiency of a. deaminase can lead to one form of severe combined immunodeficiency disease.
- a. diphosphate a. 5′-diphosphate.
- a. kinase enzyme catalyzing the transfer of a phosphate group from MgATP to a., forming MgADP and AMP. An important step in nucleoside salvage.
- a. monophosphate (AMP) specifically, a.-5′-monophosphate. See adenylic acid.
- a. nucleosidase an enzyme hydrolyzing a. to adenine and d-ribose.
- a. phosphate specifically, a. 3′- or 5′-phosphate. See adenylic acid.
- a. tetraphosphate a condensation product of a. with tetraphosphoric acid at the 5′ position.
- a. triphosphate SYN: a. 5′-triphosphate.

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aden·o·sine ə-'den-ə-.sēn, -sən n a nucleoside C10H13N5O4 that is a constituent of RNA yielding adenine and ribose on hydrolysis

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n.
a nucleoside that contains adenine and the sugar ribose and occurs in ATP. It is also used as an anti-arrhythmic drug to stop supraventricular tachycardia and restore a normal heart rhythm. As such, it needs to be injected quickly, which may fleetingly make the patient feel faint and develop chest pain. Trade name: Adenocor.

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aden·o·sine (ə-denґo-sēn) 1. a purine nucleoside, adenine linked by its N9 nitrogen to the C1 carbon of ribose. It is a component of ribonucleic acid (RNA) and its nucleotides play major roles in the reactions and regulation of metabolism. Symbol A. 2. [USP] a preparation of adenosine, which acts as a cardiac depressant of automaticity in the sinus node and conduction in the atrioventricular node and also as a vasodilator; used as an antiarrhythmic in the treatment of paroxysmal supraventricular tachycardia and as a diagnostic adjunct, in conjunction with myocardial perfusion imaging, to induce coronary artery vasodilation in patients unable to exercise adequately to undergo an exercise stress test; administered intravenously.

Medical dictionary. 2011.

Look at other dictionaries:

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  • Adénosine — Structure de l adénosine. Général Nom IUPAC 2 (6 aminopurin 9 yl) 5 (hydroxyméthyl)oxolane 3,4 diol …   Wikipédia en Français

  • Adenosine — Adénosine Adénosine Structure de l adénosine. Général Nom IUPAC 2 (6 aminopurin 9 yl) 5 (hydroxyméthyl)oxolane 3,4 diol …   Wikipédia en Français

  • adénosine — [ adenozin ] n. f. • 1919; de adén(ine), 1. ose et ine ♦ Biochim. Constituant important des noyaux cellulaires résultant de la combinaison de l adénine avec la ribose. Adénosine triphosphate. ⇒ A. T. P. ● adénosine nom féminin Acide aminé issu de …   Encyclopédie Universelle

  • adenosine — adenosine. См. аденозин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • adenosine — [ə den′ə sēn΄, ə den′əsin] n. [arbitrary blend < ADENINE + RIBOSE] a white, odorless, crystalline powder, C5H4N5·C5H9O4, obtained from the hydrolysis of yeast nucleic acid: it is a nucleoside consisting of adenine and ribose: see also ADP1,… …   English World dictionary

  • adenosine — noun /əˈdɛnəʊsɪn/ a) A nucleoside derived from adenine and ribose, found in striated muscle tissue. This reaction will replace all the adenosines with isosines. b) An instance of adenosine …   Wiktionary

  • adenosine — adenozinas statusas T sritis chemija apibrėžtis Nukleozidas. formulė C₁₀H₁₃N₅O₄ santrumpa( os) Ado, A atitikmenys: angl. adenosine rus. аденозин ryšiai: sinonimas – 9 β D ribofuranoziladeninas …   Chemijos terminų aiškinamasis žodynas

  • adenosine — The (ribo)nucleoside resulting from the combination of the base adenine (A) and the sugar D ribose. The corresponding deoxyribonucleoside is called deoxyadenosine. See: adenosine triphosphate, adenylic acid, dATP …   Glossary of Biotechnology

  • adenosine — noun Etymology: International Scientific Vocabulary, blend of adenine and ribose Date: circa 1909 a nucleoside C10H13N5O4 that is a constituent of RNA and yields adenine and ribose on hydrolysis …   New Collegiate Dictionary

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