null-cell adenoma

null-cell adenoma
a pituitary adenoma whose cells give negative results on tests for staining and hormone secretion; although classically they were considered to be composed of sparsely granulated or degranulated (nonfunctioning) cells, some contain functioning cells and may be associated with a hyperpituitary state such as acromegaly or Cushing syndrome. These tumors are often discovered clinically only when they have grown large and are pressing on surrounding structures. Called also chromophobic a.

Medical dictionary. 2011.

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