aldehyde reductase


aldehyde reductase
al·de·hyde re·duc·tase (alґdə-hīd re-dukґtās) [EC 1.1.1.21] an enzyme of the oxidoreductase class that catalyzes the reduction of aldoses to form alditols, using NADPH as an electron donor. In galactosemia due to galactokinase deficiency, catalysis of the reduction of galactose to galactitol by aldehyde reductase in the lens of the eye results in cataract formation. Called also aldose reductase.

Medical dictionary. 2011.

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