passive cutaneous anaphylaxis

passive cutaneous anaphylaxis
(PCA) a passively transferred local anaphylactic reaction used in the study of reaginic antibodies; the skin of an animal is sensitized by intradermal injection of serum from a sensitized animal, and after a 24- to 72-hour latent period the antigen and Evans blue dye are injected intravenously. Reaction of the antigen with skin-fixed antibody causes the release of histamine, which increases vascular permeability, permits leakage of the albumin-bound dye, and produces a blue spot at the site of the intradermal injection.

Medical dictionary. 2011.

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  • passive cutaneous anaphylaxis reaction — passive cutaneous anaphylaxis …   Medical dictionary

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  • local anaphylaxis — anaphylaxis confined to a limited area, e.g., passive cutaneous anaphylaxis …   Medical dictionary

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  • pCa — A way of reporting calcium ion levels; equal to the negative decadic logarithm of the calcium ion concentration. * * * pancreatic carcinoma; para chlor amphetamine; parietal cell antibody; passive cutaneous anaphylaxis; patient care… …   Medical dictionary

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