- positive anergy
- reduction in reactivity to allergens in a sensitized individual, owing to alterations in the immune response in the course of disease, as in tuberculosis.
Medical dictionary. 2011.
Medical dictionary. 2011.
Anergy — A state of immune unresponsiveness. Induced when the T cell s antigen receptor is stimulated, effectively freezing T cell responses pending a second signal from the antigen presenting cell. The delivery of the second signal by the antigen… … Medical dictionary
Mantoux test — The Mantoux skin test consists of an intradermal injection of exactly one tenth of a milliliter (mL) of PPD tuberculin … Wikipedia
Molecular mimicry — is defined as the theoretical possibility that sequence similarities between foreign and self peptides are sufficient to result in the cross activation of autoreactive T or B cells by pathogen derived peptides. Despite the promiscuity of several… … Wikipedia
Immune tolerance — or immunological tolerance is the process by which the immune system does not attack an antigen.[1] It can be either natural or self tolerance , in which the body does not mount an immune response to self antigens, or induced tolerance , in which … Wikipedia
T cell — T cells belong to a group of white blood cells known as lymphocytes, and play a central role in cell mediated immunity. They can be distinguished from other lymphocyte types, such as B cells and natural killer cells by the presence of a special… … Wikipedia
Cytotoxic T cell — Antigen presentation stimulates T cells to become either cytotoxic CD8+ cells or helper CD4+ cells. A cytotoxic T cell (also known as TC, Cytotoxic T Lymphocyte, CTL, T Killer cell, cytolytic T cell, CD8+ T cells or killer T cell) belongs to a… … Wikipedia
Central tolerance — is the mechanism by which newly developing T cells and B cells are rendered non reactive to self[1]. The concept of central tolerance was proposed in 1959 by Joshua Lederberg[2], as part of his general theory of immunity and tolerance, and is… … Wikipedia
Major histocompatibility complex — The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates that encodes MHC molecules. MHC molecules play an important role in the immune system and autoimmunity. Proteins are continually… … Wikipedia
Immune tolerance in pregnancy — or gestational/maternal immune tolerance is the absence of a maternal immune response against the fetus and placenta, which thus may be viewed as unusually successful allografts, since they genetically differ from the mother.[1] In the same way,… … Wikipedia
Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… … Wikipedia