Bruton tyrosine kinase

Bruton tyrosine kinase
(BTK) Bru·ton ty·ro·sine ki·nase (BTK) (brooґtən tiґro-sēn kiґnās) a nonreceptor tyrosine kinase (non-specific protein-tyrosine kinase, q.v.) that plays an important role in signaling in B-cell activation and differentiation; mutation has been linked to X-linked agammaglobulinemia.

Medical dictionary. 2011.

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  • Bruton agammaglobulinemia (disease) tyrosine kinase — Bru·ton agammaglobulinemia (disease), tyrosine kinase (brooґtən) [Col. Ogden Carr Bruton, American pediatrician, 1908–2003] see X linked agammaglobulinemia, under agammaglobulinemia, and see Bruton tyrosine kinase …   Medical dictionary

  • Bruton's tyrosine kinase — (or Btk) is a type of kinase enzyme implicated in the primary immunodeficiency disease X linked agammaglobulinemia (XLA). Its exact mechanism of action remains unknown, but it plays a crucial role in B cell maturation as well as mast cell… …   Wikipedia

  • Non-specific protein-tyrosine kinase — In enzymology, a non specific protein tyrosine kinase (EC number|2.7.10.2) is an enzyme that catalyzes the chemical reaction:ATP + a [protein] L tyrosine ightleftharpoons ADP + a [protein] L tyrosine phosphateThus, the two substrates of this… …   Wikipedia

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  • Bruton (disambiguation) — Bruton may refer to:Places* Bruton, a village and civil parish in Somerset, EnglandPeople* John Bruton, Ambassador of the European Union to the United States of America. * Richard Bruton, Opposition Spokesperson on Finance in Ireland. * Bill… …   Wikipedia

  • Ogden Bruton — Ogden Carr Bruton Ogden Carr Bruton (born June 14, 1908 in Mount Gilead, North Carolina; died January 20, 2003) was a pediatrician and chief of pediatrics at Walter Reed Army Hospital, where he organized the first pediatric residency at this… …   Wikipedia

  • Bruton-Tyrosinkinase — Masse/Länge Primärstruktur 658 Aminosäuren …   Deutsch Wikipedia

  • Protein kinase D1 — Protein kinase D1, also known as PRKD1, is a human gene.cite web | title = Entrez Gene: PRKD1 protein kinase D1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=5587| accessdate = ] PBB Summary section title …   Wikipedia

  • Btk — Bruton s tyrosine kinase * * * Bruton tyrosine kinase …   Medical dictionary

  • Тирозинкиназа Брутона — Структура каталитического домена тирозинкиназы Брутона Обозначения …   Википедия

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