- AMP deaminase
- An enzyme hydrolyzing adenylic acid to inosinic acid and NH3. A deficiency of A. in muscles can lead to excess fatigue following exercise. SYN: adenylic acid deaminase.
* * *AMP de·am·i·nase (de-amґĭ-nās) [EC 22.214.171.124] an enzyme of the hydrolase class that catalyzes the deamination of AMP to form inosine monophosphate. Isoenzyme A (myoadenylate deaminase) is present in large amounts in muscle tissue and is a major source of ammonium ions during muscle contraction. Deficiency of this isoenzyme, an autosomal recessive trait, is characterized by muscle fatigue following exercise. Two additional isoenzymes have been identified: isoenzyme B, found in liver, kidney, and testes, and isoenzyme C, found in heart muscle. Called also adenylate deaminase.
Medical dictionary. 2011.
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myoadenylate deaminase — Muscle AMP deaminase. See AMP deaminase. * * * myo·ad·en·yl·ate de·am·i·nase (mi″o adґən əl āt de amґĭ nās) the muscle isozyme of AMP deaminase; it is the isoenzyme A of AMP deaminase (q.v.) … Medical dictionary
adenylate deaminase — aden·yl·ate de·am·i·nase (ə denґə lāt de amґĭ nās) AMP deaminase … Medical dictionary
myoadenylate deaminase deficiency — myo·ad·en·yl·ate de·am·i·nase de·fi·cien·cy (mi″o adґən əl āt de amґĭ nās) a mild autosomal recessive disorder caused by mutation in the AMPD1 gene (locus: 1p21 p13), which encodes the muscle isoform of AMP… … Medical dictionary
Adenosine-phosphate deaminase — In enzymology, an adenosine phosphate deaminase (EC number|126.96.36.199) is an enzyme that catalyzes the chemical reaction:5 AMP + H2O ightleftharpoons 5 IMP + NH3Thus, the two substrates of this enzyme are 5 AMP and H2O, whereas its two products are … Wikipedia