dihydrolipoyllysine-residue acetyltransferase


dihydrolipoyllysine-residue acetyltransferase
di·hy·dro·lip·o·yl·lys·ine-res·i·due ac·e·tyl·trans·fer·ase (di-hi″dro-lip″o-əl-liґsēn rezґĭ-doo as″ə-tēl-transґfər-ās) [EC 2.3.1.12] an enzyme of the transferase class that is a component of the multienzyme pyruvate dehydrogenase complex (q.v.). The lipoyl group of this enzyme is reductively acetylated by pyruvate dehydrogenase (acetyl-transferring); the enzyme then catalyzes the transfer of acetyl from its lipoamide chain to coenzyme A to form acetyl CoA. Called also dihydrolipoyl transacetylase.

Medical dictionary. 2011.

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  • Dihydrolipoyllysine-residue acetyltransferase — In enzymology, a dihydrolipoyllysine residue acetyltransferase (EC number|2.3.1.12) is an enzyme that catalyzes the chemical reaction:acetyl CoA + enzyme N6 (dihydrolipoyl)lysine ightleftharpoons CoA + enzyme N6 (S acetyldihydrolipoyl)lysineThus …   Wikipedia

  • Dihydrolipoyl transacetylase — dihydrolipoyllysine residue acetyltransferase Atomic structure of a single subunit of dihydrolipoyl transacetylase from Azotobacter vinelandii that makes up the structural core of the pyruvate dehydrogenase multienzyme complex.[1] …   Wikipedia

  • Pyruvate dehydrogenase (acetyl-transferring) — In enzymology, a pyruvate dehydrogenase (acetyl transferring) (EC number|1.2.4.1) is an enzyme that catalyzes the chemical reaction:pyruvate + [dihydrolipoyllysine residue acetyltransferase] lipoyllysine ightleftharpoons [dihydrolipoyllysine… …   Wikipedia

  • List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… …   Wikipedia

  • pyruvate dehydrogenase (acetyl-transferring) — py·ru·vate de·hy·dro·gen·ase (ac·e·tyl trans·fer·ring) (piґroo vāt de hiґdro jən ās asґə təl transґfər ing) [EC 1.2.4.1] an enzyme of the oxidoreductase class that is a component of the multienzyme pyruvate… …   Medical dictionary

  • pyruvate dehydrogenase complex — a multienzyme complex consisting of multimers of the three distinct enzymes: pyruvate dehydrogenase (acetyl transferring) [EC 1.2.4.1], dihydrolipoyllysine residue acetyltransferase [EC 2.3.1.12], and dihydrolipoyl dehydrogenase [EC 1.8.1.4]. The …   Medical dictionary

  • dihydrolipoyl transacetylase — di·hy·dro·lip·o·yl trans·acet·y·lase (di hi″dro lipґo əl trans″ə setґə lās) dihydrolipoyllysine residue acetyltransferase …   Medical dictionary