(DHA) 2,8-di·hy·droxy·ad·e·nine (DHA) (di″hi-drok″se-adґə-nēn) an insoluble purine produced in excess in deficiencies of the salvage pathway of adenine catalyzed by adenine phosphoribosyltransferase; accumulation can cause crystalluria and nephrolithiasis.

Medical dictionary. 2011.

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  • 2,8-Dihydroxyadenine — IUPAC name 6 Amino 7,9 dihydro 1H purine 2,8 dione …   Wikipedia

  • 2,8-dihydroxyadenine — An insoluble minor product of adenine catabolism that is elevated in individuals with an absence of adenine phosphoribosyltransferase …   Medical dictionary

  • Adenine phosphoribosyltransferase — Adenine phosphoribosyltransferase, also known as APRT, is a human gene.cite web | title = Entrez Gene: APRT adenine phosphoribosyltransferase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=353| accessdate …   Wikipedia

  • Adenina fosforribosiltransferasa — Diagrama de cintas de un dímero de APRT humana unida a PRPP, a adenina y a ribosa 5 fosfato. En verde se puede apreciar un ion magnesio. Disponible en PDB …   Wikipedia Español

  • Adenine phosphoribosyltransferase deficiency — (also called 2,8 dihydroxyadenine urolithiasis) is an autosomal recessivecite journal |pmid=8976113 |year=1996 |month=Dec |author=Kamatani, N |title=Adenine phosphoribosyltransferase(APRT) deficiency |volume=54 |issue=12 |pages=3321–7 |issn=0047… …   Wikipedia

  • lithiasis — Formation of calculi of any kind, especially of biliary or urinary calculi. [litho + G. iasis, condition] l. conjunctivae hard nodules caused by deposition of calcareous material in areas of cellular degeneration in Henle …   Medical dictionary

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  • Jay Tischfield — [ [http://lifesci.rutgers.edu/tischlab/index.html The Tischfield’s Lab homepage] ] He is also is the scientific director of the Rutgers University Cell DNA repository, the largest university based repository in the world. [… …   Wikipedia

  • adenine — One of the two major purines (the other being guanine) found in both RNA and DNA, and also in various free nucleotides of importance to the body, such as AMP (adenylic acid), ATP, NAD+ and NADP+, and FAD; in all these smaller compounds, a. is… …   Medical dictionary

  • DHA — dehydroacetic acid; dehydroascorbic acid; dehydroepiandrosterone; dihydroacetic acid; dihydroxyacetone; district health authority * * * DHA abbr 1) dehydroepiandrosterone 2) dihydroxyacetone 3) docosahexaenoic acid * * * docosahexaenoic acid; 2,8 …   Medical dictionary