antisense

antisense
See a. DNA, a. RNA.

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an·ti·sense 'an-.tī-.sens, 'an-ti- adj having a sequence complementary to a segment of genetic material specif of, being, relating to, or possessing a sequence of DNA or RNA that is complementary to and pairs with a specific messenger RNA blocking it from being translated into protein and serving to inhibit gene function <\antisense RNA> <\antisense drug therapy to inhibit malignant cell proliferation> <\antisense research> compare MISSENSE, NONSENSE

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an·ti·sense (an″te-) (anґti-sens) pertaining to the strand of a double-stranded molecule that does not directly encode the product but is complementary to it; see under strand and RNA.

Antisense strand of DNA, complementary to the sense (coding) strand and serving as a template for RNA synthesis.


Medical dictionary. 2011.

Look at other dictionaries:

  • Antisense — (engl. etwa ‚Gegensinn‘) steht für: eine einzelsträngige RNA zur Regulation der Genexpression, siehe Antisense RNA die Leserichtung bei einzelsträngiger viraler DNA oder RNA, siehe Polarität (Virologie) Diese Seite ist eine Begrif …   Deutsch Wikipedia

  • antisense — [an′tē sens΄, an′tīsens΄] adj. Genetics of, having, being, or based on a nucleotide sequence that blocks DNA protein synthesis by binding with and inhibiting the action of specific MESSENGER RNA …   English World dictionary

  • antisense — ˌ adjective Etymology: anti (I) + sense (as in nonsense herein) : having a sequence complementary to a segment of genetic material ; specifically : of, being, relating to, or possessing a sequence of DNA or RNA that is complementary to and pairs… …   Useful english dictionary

  • antisense — adjective Etymology: anti + nonsense Date: 1977 having a sequence complementary to a segment of genetic material; specifically of, being, relating to, or possessing a sequence of DNA or RNA that is complementary to and pairs with a specific… …   New Collegiate Dictionary

  • antisense — In general the complementary strand of a coding sequence of DNA or of mRNA. Antisense RNA hybridizes with and inactivates mRNA …   Dictionary of molecular biology

  • Antisense therapy — is a form of treatment for genetic disorders or infections.When the genetic sequence of a particular gene is known to be causative of a particular disease, it is possible to synthesize a strand of nucleic acid (DNA, RNA or a chemical analogue)… …   Wikipedia

  • Antisense RNA — (aRNA) is single stranded RNA that is complementary to a messenger RNA (mRNA) strand transcribed within a cell. Antisense RNA may be introduced into a cell to inhibit translation of a complementary mRNA by base pairing to it and physically… …   Wikipedia

  • Antisense-Oligonukleotid — Antisense Oligonukleotide sind kurzkettige synthetische Nukleinsäuren. Der Name nimmt darauf Bezug, dass ihre Basensequenz entgegengesetzt (und damit „entgegen dem ursprünglichen Sinn“ = anti sense) zu einer funktionalen mRNA ist. Während dem… …   Deutsch Wikipedia

  • Antisense-Technologie —   [æntɪ sens , englisch], Verfahren zur Unterdrückung der Ablesung der genetischen Information der Zelle durch die Einführung einer natürlichen oder synthetischen Nukleotidsequenz, die komplementär zur Nukleinsäuresequenz des Zielgens ist. Die… …   Universal-Lexikon

  • antisense RNA — antisense RNA. См. антисмысловая РНК. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

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