central core disease


central core disease
an autosomal dominant form of myopathy characterized by dense, amorphous hyaline changes in the central portion of the myofibrils, which lack organelles. Onset is in infancy and causes delayed motor development, especially in the lower limbs. Called also Shy-Magee syndrome.

Medical dictionary. 2011.

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  • Central core disease — Infobox Disease Name = Central core disease Caption = Histopathologic appearance of typical central core disease: NADH TR, transverse section from the rectus femoris. Marked predominance of dark staining, high oxidative type 1 fibres with cores… …   Wikipedia

  • Central Core Disease — Klassifikation nach ICD 10 G71.2 Angeborene Myopathien Zentralfibrillenmyopathie (Central Core Krankheit) …   Deutsch Wikipedia

  • Central core disease of muscle (CCD) — One of the conditions that produces ‘floppy baby’ syndrome. CCD causes hypotonia (floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding… …   Medical dictionary

  • CCD (Central core disease of muscle) — One of the conditions that produces ‘floppy baby’ syndrome. CCD causes hypotonia (floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding… …   Medical dictionary

  • Muscle, central core disease of (CCD) — One of the conditions that produces ‘floppy baby’ syndrome. CCD causes hypotonia (inadequately toned muscles characterized by floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle… …   Medical dictionary

  • Central-Core-Myopathie — Klassifikation nach ICD 10 G71.2 Angeborene Myopathien Zentralfibrillenmyopathie (Central Core Krankheit) …   Deutsch Wikipedia

  • central core myopathy — see under disease …   Medical dictionary

  • Disease, central core, of muscle (CCD) — One of the conditions that produces ‘floppy baby’ syndrome. CCD causes hypotonia (floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding… …   Medical dictionary

  • Disease — Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the… …   Medical dictionary

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