storage pool disease

storage pool disease
any of various types of coagulopathy due to defects in the dense bodies of platelets, so that the platelets fail to release ADP in response to aggregating agents such as collagen, epinephrine, exogenous ADP, and thrombin. It is characterized by mild bleeding episodes, prolonged bleeding time, and reduced aggregation response to collagen or thrombin. One type is a component of the autosomal recessive condition Hermansky-Pudlak syndrome. Called also storage pool deficiency.

Medical dictionary. 2011.

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