patch electrode

patch electrode
a tiny electrode with a blunt tip, used in studies of membrane potentials. See also patch clamp and microelectrode.

Medical dictionary. 2011.

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  • patch clamp — A specialized and powerful variant of voltage clamp method, in which a patch electrode of relatively large tip diameter (5 m m) is pressed tightly against the plasma membrane of a cell, forming an electrically tight, gigohm seal. The current… …   Dictionary of molecular biology

  • patch clamp — a type of voltage clamp in which a patch electrode is pressed against an area of the plasma membrane of a cell, forming an electrically tight seal so that the flow of current through individual ion channels can be measured …   Medical dictionary

  • Patch clamp — The patch clamp technique is a laboratory technique in electrophysiology that allows the study of single or multiple ion channels in cells. The technique can be applied to a wide variety of cells but is especially useful in the study of excitable …   Wikipedia

  • Électrode (biologie) —  Pour l’article homonyme, voir électrode.  Principalement en neurobiologie, une électrode est un dispositif permettant de mesurer un différentiel de potentiel électrique entre deux points d un système biologique, par exemple entre l… …   Wikipédia en Français

  • whole cell patch — A variant of patch clamp technique, in which the patch electrode seals against the cell, with direct communication between the interior of the electrode and the cytoplasm …   Dictionary of molecular biology

  • inside-out patch — A variant of the patch clamp technique, in which a disc of plasma membrane covers the tip of the electrode, with the inner face of the plasma membrane facing outward, to the bath …   Dictionary of molecular biology

  • outside-out patch — A variant of patch clamp technique, in which a disc of plasma membrane covers the tip of the electrode, with the outer face of the plasma membrane facing outward, to the bath …   Dictionary of molecular biology

  • Electrophysiology — (from Greek gr. ἥλεκτρον, ēlektron , amber [see the etymology of electron ] ; gr. φύσις, physis , nature, origin ; and gr. λογία, logia ) is the study of the electrical properties of biological cells and tissues. It involves measurements of… …   Wikipedia

  • Multielectrode array — Multielectrode arrays (MEAs) or microelectrode arrays are devices that contain multiple plates or shanks through which neural signals are obtained or delivered, essentially serving as neural interfaces that connect neurons to electronic circuitry …   Wikipedia

  • Voltage clamp — The voltage clamp is used by electrophysiologists to measure the ion currents across a neuronal membrane while holding the membrane voltage at a set level. Neuronal membranes contain many different kinds of ion channels, some of which are voltage …   Wikipedia

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