acute necrotizing hemorrhagic encephalomyelitis


acute necrotizing hemorrhagic encephalomyelitis
a rare, fatal postinfection or allergic demyelinating disease of the central nervous system, having a fulminating course and occurring mainly in young adults. It is characterized by destruction of the white matter to the point of liquefaction; widespread necrosis of blood vessel walls leading to the formation of multiple small hemorrhages in the involved areas and the exudation of fibrin into the surrounding tissue; and cellular infiltration of the necrotic areas. Onset is abrupt and marked by headache, stiff neck, and confusion; these are followed by focal seizures, paralysis, progressively deepening coma, and death.

Medical dictionary. 2011.

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