aspartate

aspartate
- a. aminotransferase (AST) an enzyme catalyzing the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming α-ketoglutaric acid and l-aspartic acid; a diagnostic aid in viral hepatitis and in myocardial infarction. SYN: a. transaminase, glutamic-aspartic transaminase, glutamic-oxaloacetic transaminase, serum glutamic-oxaloacetic transaminase.
- a. ammonia-lyase a nonmammalian enzyme catalyzing the conversion of l-aspartic acid to fumaric acid, splitting out ammonia. SYN: aspartase, fumaric aminase.
- a. carbamoyltransferase an enzyme catalyzing formation of ureidosuccinate (N-carbamoyl-l-a.) and orthophosphate by the transfer of a carbamoyl moiety from carbamoylphosphate to the amino group of l-a.; participates in pyrimidine biosynthesis.
- a. kinase an enzyme catalyzing the phosphorylation by ATP of l-a. to form 4-phospho-l-a. (β-aspartyl phosphate) and ADP.
- a. transaminase SYN: a. aminotransferase.

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as·par·tate -.tāt n a salt or ester of aspartic acid

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as·par·tate (ə-spahrґtāt) a salt of aspartic acid, or aspartic acid in dissociated form.

Medical dictionary. 2011.

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  • aspartate — (= aspartic acid; Asp; D; 133D) L aspartate is one of the 20 amino acids directly coded in proteins; the free amino acid is a neurotransmitter …   Dictionary of molecular biology

  • Aspartate transaminase — Aspartate aminotransferase from Escherichia coli bound with cofactor pyridoxal 5 phosphate.[1] Identifiers …   Wikipedia

  • aspartate transaminase — n ASPARTATE AMINOTRANSFERASE * * * (AST, ASAT) as·par·tate trans·am·i·nase (AST, ASAT) (ə spahrґtāt trans amґĭ nās) [EC 2.6.1.1] an enzyme of the transferase class that catalyzes the reversible transfer of an amino group from… …   Medical dictionary

  • Aspartate aminotransférase — Aspartate amino transférase L Aspartate aminotransférase (ASAT ou AST) est une enzyme (EC 2.6.1.1) faisant partie des transaminases dont l activité est mesurée en biologie clinique lors de certaines maladies. Elle se trouve en quantité importante …   Wikipédia en Français

  • Aspartate transaminase — Aspartate amino transférase L Aspartate aminotransférase (ASAT ou AST) est une enzyme (EC 2.6.1.1) faisant partie des transaminases dont l activité est mesurée en biologie clinique lors de certaines maladies. Elle se trouve en quantité importante …   Wikipédia en Français

  • Aspartate Kinase — Enzyme de la grande famille des kinases, l aspartate kinase catalyse la transformation de l aspartate en aspartylphosphate. Il existe 3 isoenzymes connus chez E. coli. Elle est régulée de façon allostérique par L Thr et L Lys. Portail de la… …   Wikipédia en Français

  • aspartate aminotransferase — n an enzyme that promotes transfer of an amino group from glutamic acid to oxaloacetic acid and that when present in abnormally high levels in the blood is a diagnostic indication of heart attack or liver disease called also aspartate… …   Medical dictionary

  • aspartate 4-decarboxylase — Aspartate β decarboxylase; a carboxy lyase converting l aspartate to l alanine (releasing CO2); it decarboxylates aminomalonate and (in bacteria) removes SO2 from cysteinesulfinate. SEE ALSO: desulfinase …   Medical dictionary

  • aspartate aminotransferase — aspartate aminotransferase. См. аспартатаминотрансфераза. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

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