Langerhans cell histiocytosis

Langerhans cell histiocytosis
any of a group of disorders characterized by proliferation of Langerhans cells, affecting children more often than adults. Lesions may be unifocal or multifocal and may involve the bone marrow, endocrine system, or lungs (the last being more common in adults than in children). Although the cause is uncertain, these disorders are believed to arise from disturbances in regulation of the immune system. Called Langerhans cell granulomatosis. Formerly called h. X.

Medical dictionary. 2011.

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  • Langerhans cell histiocytosis — Classification and external resources Micrograph showing a Langerhans cell histiocytosis with the characteristic reniform Langerhans cells accompanied by abundant eosinophils. H E stain …   Wikipedia

  • Langerhans cell histiocytosis multifocal — Langerhans cell histiocytosis occurring as erosive accumulations of proliferating Langerhans cells, commonly within the medullary cavities of bones, but also affecting the skin, gingiva, lungs, and stomach. It most commonly affects children and… …   Medical dictionary

  • Langerhans cell histiocytosis unifocal — Langerhans cell histiocytosis occurring as a single osteolytic lesion, usually in a long or flat bone; it may be asymptomatic or may produce bone pain, tenderness, and swelling and, sometimes, pathologic fracture …   Medical dictionary

  • Langerhans cell histiocytosis — overgrowth of cells of the reticuloendothelial system. This includes disorders previously called histiocytosis X, including eosinophilic granuloma, Hand Schüller Christian disease, and Letterer Siwe disease. P. Langerhans (1847 88), German… …   Medical dictionary

  • Langerhans cell histiocytosis — overgrowth of cells of the reticuloendothelial system. This includes disorders previously called histiocytosis X, including eosinophilic granuloma, Hand Schüller Christian disease, and Letterer Siwe disease [Langerhans (1847–88), German physician …   The new mediacal dictionary

  • Langerhans cell histiocytosis — LCH. A group of rare disorders in which too many Langerhans cells (a type of white blood cell) grow in certain tissues and organs including the bones, skin, and lungs, and damage them. LCH may also affect the pituitary gland (which makes hormones …   English dictionary of cancer terms

  • Non-Langerhans cell histiocytosis — Classification and external resources MeSH D015616 Non Langerhans cell histiocytosis refers to a family of histiocytosis characterized by the absence of Langerhans cells …   Wikipedia

  • Langerhans cell — Not to be confused with the beta cells making up the islets of Langerhans. Langerhans cells are dendritic cells abundant in epidermis, containing large granules called Birbeck granules. They are normally present in lymph nodes, and can be found… …   Wikipedia

  • Langerhans cell histiocytosis acute disseminated — Letterer Siwe disease …   Medical dictionary

  • Histiocytosis, Langerhans cell — Histiocytosis in which the active histiocytes normally occur in the skin. See histiocytosis …   Medical dictionary

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