hydroxymethylglutaryl-CoA synthase

hydroxymethylglutaryl-CoA synthase
hy·droxy·meth·yl·glu·ta·ryl-CoA syn·thase (hi-drok″se-meth″əl-glooґtə-rəl ko-aґ sinґthās) [EC 2.3.3.10] an enzyme of the transferase class that catalyzes the condensation of acetyl coenzyme A and acetoacetyl coenzyme A to form 3-hydroxy-3-methylglutaryl CoA. A liver and kidney mitochondrial enzyme catalyzes the reaction as a step in ketogenesis; a cytosolic enzyme acts in the synthesis of cholesterol and other isoprenoids.

Medical dictionary. 2011.

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  • Hydroxymethylglutaryl-CoA synthase — In enzymology, a hydroxymethylglutaryl CoA synthase (EC number|2.3.3.10) is an enzyme that catalyzes the chemical reaction:acetyl CoA + H2O + acetoacetyl CoA ightleftharpoons (S) 3 hydroxy 3 methylglutaryl CoA + CoAThe 3 substrates of this enzyme …   Wikipedia

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  • 3-hydroxy-3-méthyl-glutaryl-CoA réductase — Cholestérol Cholestérol Structure du cholestérol Général Nom IUPAC 10,13 diméthyl 17 (6 méthylheptan 2 yl) 2,3,4,7,8,9,11,12,14 …   Wikipédia en Français

  • HMG-CoA réductase — Cholestérol Cholestérol Structure du cholestérol Général Nom IUPAC 10,13 diméthyl 17 (6 méthylheptan 2 yl) 2,3,4,7,8,9,11,12,14,15 …   Wikipédia en Français

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  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

  • List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia

  • Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français

  • List of EC numbers (EC 4) — This list contains a list of EC numbers for the fourth group, EC 4, lyases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 4.1: Carbon Carbon LyasesEC… …   Wikipedia

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