banding


banding
The process of differential staining of (usually) metaphase chromosomes of cells to reveal the characteristic patterns of bands that permit identification of individual chromosomes and recognition of missing segments; each of the 22 pairs of human chromosomes and the X and Y chromosomes has an identifying b. pattern.
- BrDu-b. labeling of chromosomes in proliferating tissue by adding an excess of bromodeoxyuridine, which replaces the uridine incorporated in RNA and fluoresces in ultraviolet light; the bands result from sister chromatid exchanges.
- high-resolution b. b., especially in prophase, which increases the clarity and number of discernible chromosome bands.
- NOR-b. a procedure which utilizes a silver stain that preferentially accumulates in the nucleoli-organizing regions, i.e., the satellite regions of the acrocentric chromosomes.
- prometaphase b. b. done in the stage of mitosis intermediate between prophase and metaphase.
- pulmonary artery b. a surgical method of decreasing pulmonary blood flow and thereby volume overload of the left ventricle, alleviating CHF in certain congenital heart defects.
- reverse b. See R-b. stain.

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band·ing (bandґing) 1. the act of encircling and binding with a thin strip of material. 2. chromosome b.

Medical dictionary. 2011.