non-nucleoside reverse transcriptase inhibitor


non-nucleoside reverse transcriptase inhibitor
(NNRTI) see reverse transcriptase i.

Medical dictionary. 2011.

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  • non-nucleoside reverse transcriptase inhibitor — noun an antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs • Syn: ↑NNRTI • Hypernyms: ↑reverse transcriptase inhibitor • Hyponyms: ↑delavirdine,… …   Useful english dictionary

  • Discovery and development of non-nucleoside reverse-transcriptase inhibitors — Non nucleoside reverse transcriptase inhibitors (NNRTIs) are antiretroviral drugs used in the treatment of human immunodeficiency virus (HIV). NNRTIs inhibit reverse transcriptase (RT), an enzyme that controls the replication of the genetic… …   Wikipedia

  • reverse transcriptase inhibitor — noun an antiviral drug that inhibits the action of reverse transcriptase in retroviruses such as HIV • Hypernyms: ↑antiviral, ↑antiviral agent, ↑antiviral drug • Hyponyms: ↑non nucleoside reverse transcriptase inhibitor, ↑NNRTI, ↑nucl …   Useful english dictionary

  • Reverse-transcriptase inhibitor — Reverse transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection, tumors,[1] and cancer.[2] RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase enzyme that retroviruses need to reproduce.… …   Wikipedia

  • Reverse transcriptase inhibitor — Reverse transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection, tumors [ [http://jcem.endojournals.org/cgi/content/full/90/10/5663/F1 Reverse Transcriptase Inhibitors Down Regulate Cell Proliferation in… …   Wikipedia

  • reverse transcriptase inhibitor — n an agent that inhibits the activity of a reverse transcriptase esp a drug (as AZT) that acts by inhibiting retroviral reverse transcription * * * a substance that blocks activity of the reverse transcriptase of a retrovirus and is used as an… …   Medical dictionary

  • Reverse transcriptase — Protbox Name=Reverse Transcriptase Photo=1HMV.png|250px Caption=3D model of HIV reverse transcriptase HGNCid = Symbol = AltSymbols = Chromosome = Arm = Band = LocusSupplementaryData = Gene= Gene type= Protein length= Molecular weight= Structure=… …   Wikipedia

  • Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors — (NRTIs and NtRTIs) began in the 1980s when the AIDS epidemic hit Western societies. NRTIs inhibit the reverse transcriptase (RT), an enzyme that controls the replication of the genetic material of the human immunodeficiency virus (HIV). The first …   Wikipedia

  • Nucleoside analogue — Nucleoside analogues are a range of antiviral products used to prevent viral replication in infected cells. The most commonly used is Acyclovir, although its inclusion in this category is uncertain, as it contains only a partial nucleoside… …   Wikipedia

  • Nichtnukleosidische Reverse-Transkriptase-Inhibitoren — (engl. Non Nucleoside Reverse Transcriptase Inhibitor, NNRTI) sind Arzneistoffe aus der Gruppe der Virustatika. Der erste Wirkstoff wurde 1990 entwickelt. Es handelt sich um Wirkstoffe, die das virale Enzym Reverse Transkriptase inhibieren und… …   Deutsch Wikipedia