phosphodiesterase inhibitor

phosphodiesterase inhibitor
any of a class of drugs that inhibit the activity of phosphodiesterases, each agent having a different effect because of differing affinities for the various phosphodiesterase fractions; the class includes amrinone, dipyridamole, enoximone, milrinone, papaverine, and theophylline.

Medical dictionary. 2011.

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  • Phosphodiesterase inhibitor — A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), therefore preventing the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and… …   Wikipedia

  • Phosphodiesterase-5-Inhibitor — Phosphodiesterase 5 Hemmer (auch Phosphodiesterase V Hemmer, PDE 5 Hemmer) sind Substanzen, die das cGMP abbauende Enzym Phosphodiesterase V hemmen und somit die Konzentration von intrazellulärem cGMP (zyklisches Guanosinmonophosphat) erhöhen.… …   Deutsch Wikipedia

  • Phosphodiesterase-V-Inhibitor — Phosphodiesterase 5 Hemmer (auch Phosphodiesterase V Hemmer, PDE 5 Hemmer) sind Substanzen, die das cGMP abbauende Enzym Phosphodiesterase V hemmen und somit die Konzentration von intrazellulärem cGMP (zyklisches Guanosinmonophosphat) erhöhen.… …   Deutsch Wikipedia

  • Phosphodiesterase-5-Hemmer — (auch Phosphodiesterase V Hemmer, PDE 5 Hemmer) sind Substanzen, die das cGMP abbauende Enzym Phosphodiesterase V hemmen und somit die Konzentration von intrazellulärem cGMP (zyklisches Guanosinmonophosphat) erhöhen. Sie verursachen unter anderem …   Deutsch Wikipedia

  • Phosphodiesterase-V-Hemmer — Phosphodiesterase 5 Hemmer (auch Phosphodiesterase V Hemmer, PDE 5 Hemmer) sind Substanzen, die das cGMP abbauende Enzym Phosphodiesterase V hemmen und somit die Konzentration von intrazellulärem cGMP (zyklisches Guanosinmonophosphat) erhöhen.… …   Deutsch Wikipedia

  • Phosphodiesterase-5 — nach PDB  …   Deutsch Wikipedia

  • Phosphodiesterase 2 — The PDE2 (phosphodiesterase 2) enzyme is one of 21 different phosphodiesterases (PDE) found in mammals. These different PDEs can be subdivided to 11 families (PDE1 – PDE11). The different PDEs of the same family are functionally related despite… …   Wikipedia

  • Phosphodiesterase — A phosphodiesterase is any enzyme that breaks a phosphodiester bond. Usually, people speaking of phosphodiesterase are referring to cyclic nucleotide phosphodiesterases, which have great clinical significance and are described below. However,… …   Wikipedia

  • Phosphodiesterase 4 — Two types of the enzyme phosphodiesterase 4 (PDE4) are known: PDE4A PDE4B See also Phosphodiesterase PDE4 inhibitor This article includes a list of related items that share the same name (or similar names) …   Wikipedia

  • PDE4 inhibitor — Piclamilast, a common PDE4 inhibitor A phosphodiesterase type 4 inhibitor, commonly referred to as a PDE4 inhibitor, is a drug used to block the degradative action of phosphodiesterase 4 (PDE4) on cyclic adenosine monophosphate (cAMP). It is a… …   Wikipedia

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