angioimmunoblastic lymphadenopathy

angioimmunoblastic lymphadenopathy
angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) a systemic disorder resembling lymphoma, characterized by fever, night sweats, and weight loss; generalized lymphadenopathy with a mixed cellular infiltrate of lymphocytes, immunoblasts, and plasma cells that alters or effaces the nodal architecture; hepatosplenomegaly; maculopapular rash; polyclonal hypergammaglobulinemia; and Coombs-positive hemolytic anemia. It is considered to be a nonmalignant hyperimmune reaction to chronic antigenic stimulation; there is proliferation of B cells accompanied by profound deficiency of T cells. The disease follows a progressive but variable course, with some patients surviving a long time but others developing infections that can be fatal. Called also immunoblastic l.

Medical dictionary. 2011.

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  • immunoblastic lymphadenopathy — im·mu·no·blas·tic lymphadenopathy .im yə nō blas tik , im .yü nō n a disease characterized by fever, weight loss, sweating spells, rash, itching, proliferation of small blood vessels and of immunoblasts, generalized lymphadenopathy, and… …   Medical dictionary

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