omalizumab

omalizumab
oma·liz·u·mab (o″mə-lizґə-mab) a recombinant, DNA-derived monoclonal antibody that binds selectively to immunoglobulin E, prevents IgE from binding to mast cells and basophils, and thus decreases allergic reactions; used in treatment of asthma and administered by injection.

Medical dictionary. 2011.

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  • Omalizumab — Masse/Länge Primärstruktur 145,1 kDa …   Deutsch Wikipedia

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  • omalizumab — noun A monoclonal antibody used mainly in allergy related asthma therapy with the purpose of reducing allergic hypersensitivity …   Wiktionary

  • omalizumab — n. a monoclonal antibody used in the treatment of severe allergic asthma that has not responded to standard therapy. It acts by binding to IgE, an immunoglobulin that mediates the allergic response. It is administered by subcutaneous injection.… …   The new mediacal dictionary

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  • Monoclonal antibodies — A general representation of the methods used to produce monoclonal antibodies. Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique… …   Wikipedia

  • Immunoglobulin E — In biology, Immunoglobulin E (IgE) is a class of antibody (or immunoglobulin isotype ) that has only been found in mammals. It plays an important role in allergy, and is especially associated with type 1 hypersensitivity. [cite journal… …   Wikipedia

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