calcitriol


calcitriol
1α,25-Dihydroxycholecalciferol (thus, a 1,3,25-triol); formation of c. is the second step in the biological conversion of vitamin D3 to its active form; it is more potent than calcidiol.

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cal·ci·tri·ol .kal-sə-'trī-.ȯl, -.ōl n a physiologically active metabolic derivative C27H44O3 of cholecalciferol that is synthesized in the liver and kidney and stimulates the intestinal absorption of calcium called also 1,25-dihydroxycholecalciferol

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cal·ci·tri·ol (kal″sĭ-triґol) 1. 1,25-dihydroxycholecalciferol. 2. a preparation of this compound, used in the treatment of hypocalcemia, hypophosphatemia, rickets, and osteodystrophy associated with a variety of disorders, such as chronic renal failure and hypoparathyroidism. Administered orally or intravenously.

Medical dictionary. 2011.

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  • Calcitriol — Systematic (IUPAC) name (1R,3S) 5 [2 [(1R,3aR,7aS) 1 [(2R) 6 hydroxy 6 methyl heptan 2 yl] 7a methyl 2,3,3a,5,6,7 hexahydro 1H inden 4 ylidene]ethylidene] 4 methylidene cyclohexane 1,3 diol …   Wikipedia

  • Calcitriol — Structure du calcitriol Général Nom IUPAC (1R,3S) 5 [2 [(1R,3aR,7aS) 1 [(2R) 6 hydroxy 6 méthyl …   Wikipédia en Français

  • Calcitriol — El calcitriol (DCI) o 1 alpha,25 dihidroxicolecalciferol (abeviado1,25 (OH)2D3) es la forma activa de la vitamina D que se encuentra en el cuerpo (vitamina D3). Lo producen los riñones que hidrolizan del 25 hidroxicolecalciferol (25 OHD, o… …   Wikipedia Español

  • calcitriol — 1,25 dihidroxivitamina D3, forma activa de la vitamina D. Es necesaria para la síntesis de las proteínas que transportan el Ca++. estructura química [véase http://www.iqb.es/diccio/c/ca.htm#calcitriol] Diccionario ilustrado de Términos Médicos..… …   Diccionario médico

  • Calcitriol — ⇒ Calciferol …   Deutsch wörterbuch der biologie

  • Calcitriol — Strukturformel Allgemeines Freiname Calcitriol Andere Namen …   Deutsch Wikipedia

  • calcitriol — The active form of vitamin D. Calcitriol is formed in the kidneys or made in the laboratory. It is used as a drug to increase calcium levels in the body in order to treat skeletal and tissue related calcium deficiencies caused by kidney or… …   English dictionary of cancer terms

  • calcitriol — (= 1a, 25 dihydroxyvitamin D3.) The form of vitamin D3 that is biologically active in intestinal transport and calcium resorption by bone …   Dictionary of molecular biology

  • calcitriol — /kal si tree awl , ol /, n. 1. Biochem. a vitamin D compound, C27H44O3, occurring in humans as a hormone derived from cholesterol, that acts in the regulation and absorption of calcium. 2. Pharm. a preparation of this compound, used in the… …   Universalium

  • calcitriol — noun The active metabolite 1,25 dihydroxycholecalciferol of vitamin D3 that is involved in the absorption of calcium …   Wiktionary