- lipoxygenase pathway
- a pathway for the formation of leukotrienes and hydroxyeicosatetraenoic acids from arachidonic acid. It is initiated by oxidation of arachidonic acid by arachidonate lipoxygenases, and the reactions occur in the cytosol of leukocytes, mast cells, platelets, and lung tissue cells.
Lipoxygenase pathway of leukotriene and hydroxyeicosatetraenoic acid synthesis. HPETE, hydroperoxyeicosatetraenoic acid; HETE, hydroxyeicosatetraenoic acid; LT, leukotriene.
Medical dictionary. 2011.
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Arachidonate 5-lipoxygenase — (5 lipoxygenase, 5 LO or Alox5) is a human enzyme, member of the lipoxygenase family. It transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases.ubstrates and productsEFA substrates and… … Wikipedia
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arachidonate 12-lipoxygenase — arach·i·don·ate 12 lip·oxy·gen·ase (ə rakґĭ don″āt lĭ pokґsə jən ās) [EC 126.96.36.199] an enzyme of the oxidoreductase class that catalyzes the oxidation of arachidonate at the 12 position to form 12… … Medical dictionary
leukotriene pathway — the part of the lipoxygenase pathway that synthesizes leukotriene … Medical dictionary
Arachidonat-5-Lipoxygenase — Vorhandene Strukturdaten: PDB … Deutsch Wikipedia
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