phosphatidylcholine–sterol O-acyltransferase

phosphatidylcholine–sterol O-acyltransferase
phos·pha·ti·dyl·cho·line–ster·ol O-ac·yl·trans·fer·ase (fos″fə-ti″dəl-koґlēn sterґol a″səl-transґfər-ās) [EC 2.3.1.43] an enzyme of the transferase class, secreted by the liver, that catalyzes the formation of cholesteryl esters in high-density lipoproteins by transferring long-chain fatty acid residues from phosphatidylcholine to a sterol. The reaction is a step in the synthesis of lipoproteins. Deficiency of the enzyme, an autosomal recessive trait, is called lecithin–cholesterol acyltransferase (LCAT) deficiency. Called also lecithin–cholesterol acyltransferase.

Medical dictionary. 2011.

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  • lecithin–cholesterol acyltransferase — (LCAT) lec·i·thin–cho·les·ter·ol ac·yl·trans·fer·ase (LCAT) (lesґĭ thin kə lesґtər ol a″səl transґfər ās) phosphatidylcholine–sterol O acyltransferase …   Medical dictionary

  • LCAT — Abbreviation for lecithin cholesterol acyltransferase. * * * lecithin cholesterol acyltransferase * * * lecithin cholesterol acyltransferase; see phosphatidylcholine–sterol O acyltransferase …   Medical dictionary

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