antigen-antibody reaction


antigen-antibody reaction
the reversible binding of antigen to homologous antibody brought about by the formation of weak bonds between antigenic determinants on antigen molecules and antigen binding sites on immunoglobulin molecules. Certain effects, e.g., precipitation and agglutination reactions and viral neutralization, result from the binding itself; other effects, e.g., complement activation and opsonization, result from conformational changes that occur in immunoglobulin molecules with antigen binding and enable them to interact with complement proteins and Fc receptors on phagocytes.

Medical dictionary. 2011.

Look at other dictionaries:

  • antigen-antibody complex — (= immune complex) The product of the reaction of antigen and immunoglobulin. If the antigen is polyvalent the complex may be insoluble; see also glomerulonephritis, Arthus reaction, Type III hypersensitivity. Immune complexes activate complement …   Dictionary of molecular biology

  • reaction — 1. The response of a muscle or other living tissue or organism to a stimulus. 2. The color change effected in litmus and certain other organic pigments by contact with substances such as acids or alkalies; also the property that such substances… …   Medical dictionary

  • Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… …   Wikipedia

  • Antibody — An ti*bod y ([a^]n t[i^]*b[o^]d [y^]), n. 1. (Med., Physiol. Chem.) Any of various bodies or substances in the blood which act in antagonism to harmful foreign bodies, as toxins or the bacteria producing the toxins. Normal blood serum apparently… …   The Collaborative International Dictionary of English

  • antibody — /an ti bod ee/, n., pl. antibodies. 1. any of numerous Y shaped protein molecules produced by B cells as a primary immune defense, each molecule and its clones having a unique binding site that can combine with the complementary site of a foreign …   Universalium

  • Antigen — Each antibody binds to a specific antigen; an interaction similar to a lock and key. An antigen is a foreign molecule that, when introduced into the body, triggers the production of an antibody by the immune system. The immune system will then… …   Wikipedia

  • reaction of identity — a reaction pattern seen in double diffusion in two dimensions: the precipitin lines between the antigen wells and the antiserum well stop at their point of intersection, indicating that the antigen samples are identical. See also r. of… …   Medical dictionary

  • antibody — An immunoglobulin molecule produced by B lymphoid cells with a specific amino acid sequence evoked in humans or other animals by an antigen (immunogen). These molecules are characterized by reacting specifically with the antigen in some… …   Medical dictionary

  • antigen — Any substance that, as a result of coming in contact with appropriate cells, induces a state of sensitivity and/or immune responsiveness after a latent period (days to weeks) and that reacts in a demonstrable way with antibodies and/or immune… …   Medical dictionary

  • Antigen - Antikörper - Bindung — Antikörper Molekül: schwere Ketten (rot), leichte Ketten (gelb). Antikörper (Immunglobuline, im internationalen Sprachgebrauch auch Immunoglobulin) sind Proteine (Eiweiße) aus der Klasse der Globuline, die in Wirbeltieren als Reaktion auf… …   Deutsch Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.