- wheal and erythema reaction
- wheal and flare reaction the characteristic local cutaneous reaction consisting of an elevated, blanched wheal surrounded by a spreading â€œflareâ€ of erythema that occurs within a few minutes at the site of a minor nonpenetrating skin injury and also in response to administration of allergen to an atopic individual; it is caused by release of histamine from mast cells.
Medical dictionary. 2011.
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