receptor protein serine/threonine kinase

receptor protein serine/threonine kinase
re·cep·tor pro·tein ser·ine/thre·o·nine ki·nase (re-sepґtər proґtēn sērґēn threґo-nēn kiґnās) [EC 2.7.11.30] a group comprising those protein-serine/threonine kinases with a transmembrane domain. Each occurs as a pair of different subunits, with each subunit having a cytoplasmic kinase domain. When brought together by binding their dimeric protein ligands (e.g., transforming growth factorβ, activins, inhibins, bone morphogenetic proteins), the subunits act together to initiate signaling cascades by activating cytoplasmic transcription factors that regulate genes required for control of cellular proliferation and differentiation. Cf. non-specific serine/threonine protein kinase.

Medical dictionary. 2011.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • Receptor protein serine/threonine kinase — In enzymology, a receptor protein serine/threonine kinase (EC number|2.7.11.30) is an enzyme that catalyzes the chemical reaction:ATP + [receptor protein] ightleftharpoons ADP + [receptor protein] phosphateThus, the two substrates of this enzyme… …   Wikipedia

  • protein-serine/threonine kinase — pro·tein ser·ine/thre·o·nine ki·nase (proґtēn sērґēn threґo nēn kiґnās) [EC 2.7.11] any of the protein kinases that phosphorylate specific serine or threonine residues in proteins. The group is divided into receptor… …   Medical dictionary

  • non-specific serine/threonine protein kinase — non spe·cif·ic ser·ine/thre·o·nine pro·tein ki·nase (non″spə sifґik sērґēn threґo nēn proґtēn kiґnās) [EC 2.7.11.1] a group comprising those protein serine/threonine kinases that do not have a transmembrane… …   Medical dictionary

  • Non-specific serine/threonine protein kinase — In enzymology, a non specific serine/threonine protein kinase (EC number|2.7.11.1) is an enzyme that catalyzes the chemical reaction:ATP + a protein ightleftharpoons ADP + a phosphoproteinThus, the two substrates of this enzyme are ATP and… …   Wikipedia

  • Protein kinase A — In cell biology, Protein kinase A (PKA) refers to a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP dependent protein kinase (EC 2.7.11.11). Protein kinase A has several functions… …   Wikipedia

  • Mitogen-activated protein kinase — Identifiers EC number 2.7.11.24 CAS number 142243 02 5 …   Wikipedia

  • Dual-specificity kinase — Identifiers EC number 2.7.12.1 CAS number 134549 83 0 …   Wikipedia

  • Phosphoinositide-dependent kinase-1 — 3 phosphoinositide dependent protein kinase 1 PDB rendering based on 1h1w …   Wikipedia

  • Ca2+/calmodulin-dependent protein kinase — Calcium/calmodulin dependent protein kinase II association domain crystal structure of calcium/calmodulin dependent protein kinase Identifiers Symbol CaMKII AD …   Wikipedia

  • Mitogen-activated protein kinase 9 — Rendering based on PDB 3E7O …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”