RNA-directed RNA polymerase


RNA-directed RNA polymerase
RNA-di·rect·ed RNA po·lym·er·ase (dĭ-rekґtəd pə-limґər-ās) [EC 2.7.7.48] an enzyme of the transferase class that catalyzes the template-directed step-by-step addition of ribonucleotides to the 3′ end of a growing RNA chain, using a single-stranded RNA template. The reaction is important for transcription, and in some cases replication, of RNA in most RNA viruses except retroviruses.

Medical dictionary. 2011.

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  • RNA-dependent RNA polymerase — (RDRP), or RNA replicase, is an enzyme that catalyzes the replication of RNA from an RNA template. This is in contrast to a typical RNA polymerase, which catalyzes the transcription of RNA from a DNA template.Viral RDRPs were discovered in the… …   Wikipedia

  • RNA-directed DNA polymerase — RNA di·rect·ed DNA po·lym·er·ase (dĭ rekґtəd pə limґər ās) [EC 2.7.7.49] an enzyme of the transferase class that catalyzes the template directed, step by step addition of deoxyribonucleotides to the 3′ end of a DNA… …   Medical dictionary

  • RNA polymerase II — (also called RNAP II and Pol II) is an enzyme found in eukaryotic cells. It catalyzes the transcription of DNA to synthesize precursors of mRNA and most snRNA and microRNA. [cite journal | author = Kronberg, R.D. | title = Eukaryotic… …   Wikipedia

  • RNA polymerase — RNAP from T. aquaticus pictured during elongation. Portions of the enzyme were made transparent so as to make the path of RNA and DNA more clear. The magnesium ion (yellow) is located at the enzyme active site. RNA polymerase (RNAP or RNApol) is… …   Wikipedia

  • RNA polymerase — A polymerase is an enzyme that catalyzes the joining of many smaller molecules (called monomers) to form a big molecule (a macromolecule). RNA polymerase is a unique enzyme that makes (synthesizes) the macromolecule RNA using DNA as the template …   Medical dictionary

  • RNA polymerase II subunit B4 — DNA directed RNA polymerase II polypeptide D (or subunit B4), also known as POLR2D, is a human gene. PBB Summary section title = summary text = This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for… …   Wikipedia

  • (RNA-polymerase)-subunit kinase — In enzymology, a [RNA polymerase] subunit kinase (EC number|2.7.11.23) is an enzyme that catalyzes the chemical reaction:ATP + [DNA directed RNA polymerase] ightleftharpoons ADP + phospho [DNA directed RNA polymerase] Thus, the two substrates of… …   Wikipedia

  • DNA-directed RNA polymerase — DNA di·rect·ed RNA po·lym·er·ase (dĭ rekґtəd pə limґər ās) [EC 2.7.7.6] any of the enzymes of the transferase class that catalyze the template directed step by step addition of ribonucleotides to the 3′ end of a… …   Medical dictionary

  • DNA-directed DNA polymerase — DNA di·rect·ed DNA po·lym·er·ase (dĭ rekґtəd pə limґər ās) [EC 2.7.7.7] any of the enzymes of the transferase class that catalyze the template directed, step by step addition of deoxyribonucleotides to the 3′ end of …   Medical dictionary

  • RNA interference — (RNAi) is a mechanism that inhibits gene expression at the stage of translation or by hindering the transcription of specific genes. RNAi targets include RNA from viruses and transposons (significant for some forms of innate immune response), and …   Wikipedia


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