Papanicolaou stain

Papanicolaou stain
a method of staining smears of secretions from the respiratory, digestive, or genitourinary tract for examination of exfoliated cells, to detect the presence of a malignant process; used in the Papanicolaou test (see under test).

Papanicolaou stain showing clusters of cells with foamy or vacuolated cytoplasm in a fine-needle aspiration biopsy specimen of adenocarcinoma.


Medical dictionary. 2011.

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  • Papanicolaou stain — showing a low grade squamous intraepithelial lesion (LSIL). Pap test. Papanicolaou stain (also Papanicolaou s stain and Pap stain) is a multichromatic staining histological technique developed by George Papanikolaou, the father of cytopathology.… …   Wikipedia

  • Papanicolaou stain test (smear) — Pap·a·nic·o·laou stain, test (smear) (pap″ə nikґo la oo) [George Nicolas Papanicolaou, Greek physician and anatomist in the United States, 1883–1962] see under test and see Stains and Staining Methods, under stain …   Medical dictionary

  • stain — 1. To discolor. 2. To color; to dye. 3. A discoloration. 4. A dye used in histologic and bacteriologic technique. 5. A procedure in which a dye or combination of dyes and reagents is used to color the constituents of cells and tissues. For… …   Medical dictionary

  • Papanicolaou's stain — A complex stain for detecting malignant cells in cervical smears. Contains in separate staining stages (a) haematoxylin, (b) Orange G phosphotungstic acid c) Light green, Bismarck Brown, Eosin and phosphotungstic acid …   Dictionary of molecular biology

  • Papanicolaou — George N., Greek U.S. physician, anatomist, and cytologist, 1883–1962. See Pap smear, Pap test, P. examination, P. smear, P. smear test, P. stain …   Medical dictionary

  • H&E stain — H E stain, HE stain or hematoxylin and eosin stain, is a popular staining method in histology. It is the most widely used stain in medical diagnosis; for example when a pathologist looks at a biopsy of a suspected cancer, the histological section …   Wikipedia

  • Cyto-Stain — Cyto Stain, or CytoStain, is commercially available mix of staining dyes for polychromatic staining in histology. It provides results comparable to Papanicolaou staining, but in less number of operations and in shorter time. It is used in… …   Wikipedia

  • Coloration de Papanicolaou — (Texte à traduire) w:en:Pap stain showing w:en:urothelial carcinoma. Urine cytology specimen. La coloration de Papanicolaou est une coloration utilisée en cytologie …   Wikipédia en Français

  • test — 1. To prove; to try a substance; to determine the chemical nature of a substance by means of reagents. 2. A method of examination, as to determine the presence or absence of a definite disease or of some substance in any of the fluids, tissues,… …   Medical dictionary

  • Staining — is an auxiliary technique used in microscopy to enhance contrast in the microscopic image.In biochemistry it involves adding a class specific (DNA, proteins, lipids, carbohydrates) dye to a substrate to qualify or quantify the presence of a… …   Wikipedia

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