autoimmune lymphoproliferative syndrome

autoimmune lymphoproliferative syndrome
(ALPS) a hereditary disorder of lymphocyte apoptosis that results in the accumulation of large numbers of mature lymphocytes in the lymph nodes and spleen, appearing during childhood and characterized by massive lymphadenopathy, splenomegaly, and autoimmune hemolytic anemia and other cytopenias.

Medical dictionary. 2011.

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