topotecan hydrochloride

topotecan hydrochloride
to·po·te·can hy·dro·chlo·ride (to″po-teґkan) a cytotoxic topoisomerase inhibitor derived from camptothecin, acting by preventing the rejoining of DNA strands following breakage by DNA topoisomerase; this leads to double-strand DNA breakage and cell death. Used as a secondary agent in treatment of metastatic ovarian carcinoma and refractory small cell lung carcinoma; administered by intravenous infusion.

Medical dictionary. 2011.

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  • List of oncology-related terms — This is a list of terms related to oncology. The original source for this list was the U.S. National Cancer Institute s public domain Dictionary of Cancer Terms . NOTOC 1 * 10 propargyl 10 deazaaminopterin * 12 O tetradecanoylphorbol 13 acetate * …   Wikipedia

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