clofibrate

clofibrate
An antilipemic agent that reduces plasma levels of cholesterol, triglycerides, and uric acid; used in the treatment of hypercholesterolemia and atherosclerosis.

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clo·fi·brate klō-'fīb-.rāt, -'fib- n a synthetic drug C12H15ClO3 used esp. to lower abnormally high concentrations of fats and cholesterol in the blood

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clo·fi·brate (klo-fiґbrāt) [USP] a fibric acid derivative with antihyperlipidemic activity, used to reduce elevated serum lipids, administered orally.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Clofibrate — Systematic (IUPAC) name ethyl 2 (4 chlorophenoxy) 2 methylpropanoate Clinical data AHFS/Drugs.com …   Wikipedia

  • Clofibrate — Général Nom IUPAC 2 (4 chlorophénoxy) 2 méthylpropanoate d éthyle No CAS …   Wikipédia en Français

  • clofibrate — ● clofibrate nom masculin Médicament agissant sur la synthèse des lipoprotéines, dont il abaisse la teneur dans le sang. (Il diminue le taux de cholestérol, des triglycérides et des lipides totaux sanguins.) …   Encyclopédie Universelle

  • clofibrate — [klō fī′brāt΄, klōfib′rāt΄] n. a drug, C12H15ClO3, taken to reduce the level of lipids, esp. cholesterol, in the blood …   English World dictionary

  • clofibrate — noun a drug (trade name Atromid S) that reduces lipids in the blood serum; used to treat some cardiovascular diseases • Syn: ↑Atromid S • Usage Domain: ↑trade name (for: ↑Atromid S) • Hypernyms: ↑medicine …   Useful english dictionary

  • clofibrate — noun Etymology: perhaps from chlor + fibr + 1 ate Date: 1964 a compound C12H15ClO3 used especially to lower abnormally high concentrations of fats and cholesterol in the blood …   New Collegiate Dictionary

  • clofibrate — /kloh fuy brayt, fib rayt/, n. Pharm. a substance, C12H15ClO3, used principally to reduce elevated plasma triglyceride and cholesterol levels. [1960 65; clofibr(ic acid) (perh. C(H)LO(RO) 2 + FIBR + IC) + ATE2] * * * …   Universalium

  • clofibrate — noun A synthetic fibrate, ethyl 2 (4 chlorophenoxy) 2 methylpropanoate …   Wiktionary

  • clofibrate — clo·fi·brate …   English syllables

  • Aluminium clofibrate — drugbox IUPAC name = CAS number = 24818 79 9 ATC prefix = C10 ATC suffix = AB03 PubChem = 6328223 DrugBank = C=20|H=24|Al=1|Cl=2|O=7 molecular weight = 474.287 g/mol bioavailability = protein bound = metabolism = Hydrolyzed to clofibric acid and… …   Wikipedia

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