conglutinin

conglutinin
Bovine serum protein that, when absorbed by erythrocyte-antibody-complement complexes, causes them to agglutinate; it is comparatively thermostable and apparently dissociates when diluted with physiologic saline solution. SYN: bovine colloid.

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con·glu·ti·nin kən-'glüt-ən-ən, (')kän- n a heat-stable protein of bovine serum that combines with red blood cells which have been treated with antibody and that causes rapid strong agglutination followed by lysis

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con·glu·ti·nin (kən-glooґtĭ-nin) a nonimmunoglobulin bovine serum protein that aggregates immune complexes with conglutinogen activity (inactivated C3b) in the presence of divalent cations. It has been used as an indicator system, replacing complement fixation, in serologic tests, and in the detection of immune complexes. Not to be confused with immunoconglutinin.

Medical dictionary. 2011.

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  • Conglutinin — collectin sub family member 8 (conglutinin) Identifiers Symbol COLEC8 Entrez 50638 HUGO …   Wikipedia

  • conglutinin — Protein present in serum that causes agglutination of antibody antigen complement complexes; binds C3b …   Dictionary of molecular biology

  • conglutinin — con·glutinin …   English syllables

  • conglutinin — kən, (ˈ)kän+ noun ( s) Etymology: International Scientific Vocabulary com + glutinin, from glutin + in; originally formed as German konglutinin 1. : a heat stable component of bovine serum that combines with red blood cells which have been… …   Useful english dictionary

  • immune conglutinin — immunoconglutinin …   Medical dictionary

  • immunoconglutinin — An autoantibody like immunoglobulin (IgM) formed in animals (or man) against their own complement following injection of complement containing complexes or sensitized bacteria. * * * im·mu·no·con·glu·ti·nin kən glüt ən in n an autoantibody formed …   Medical dictionary

  • conglutination reaction — a characteristic agglutination reaction obtained by a mixture of conglutinin, cells (e.g., bacteria or red cells), fresh complement, and a cell specific immune serum from which the agglutinins have been removed by absorption. See conglutinin …   Medical dictionary

  • Collectin — Collectins are soluble pattern recognition receptors (PRRs) belonging to the superfamily of collagen containing C type lectins. Eight collectins have been identified including mannan binding lectin (MBL), surfactant protein A (SP A), surfactant… …   Wikipedia

  • collectin — Family of collagenous lectins believed to play an important part in first line defence by binding to viruses and by opsonizing yeasts and bacteria. Contain a collagen like region and a C type lectin domain. Pulmonary surfactant proteins A and D… …   Dictionary of molecular biology

  • colloid — 1. Aggregates of atoms or molecules in a finely divided state (submicroscopic), dispersed in a gaseous, liquid, or solid medium, and resisting sedimentation, diffusion, and filtration, thus differing from precipitates. SEE ALSO: hydrocolloid …   Medical dictionary

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