cross-matching


cross-matching
1. A test for incompatibility between donor and recipient blood, carried out prior to transfusion to avoid potentially lethal hemolytic reactions between the donor's red blood cells and antibodies in the recipient's plasma, or the reverse; performed by mixing a sample of red blood cells of the donor with plasma of the recipient (major crossmatch) and the red blood cells of the recipient with the plasma of the donor (minor crossmatch). Incompatibility is indicated by clumping of red blood cells and contraindicates use of the donor's blood. 2. In allotransplantation of solid organs ( e.g., kidney), a test for identification of antibody in the serum of potential allograft recipients which reacts directly with the lymphocytes or other cells of a potential allograft donor; presence of these antibodies usually, if not always, contraindicates the performance of the transplantation because virtually all such grafts will be subject to a hyperacute type of rejection.

Medical dictionary. 2011.

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  • Cross-matching — Intervention MeSH D001788 Cross matching blood, in transfusion medicine, refers to the complex testing that is performed prior to a blood transfusion, to determine if the donor s blood is compatible with the blood of an intended …   Wikipedia

  • cross-matching — crossˈ matching noun • • • Main Entry: ↑cross …   Useful english dictionary

  • cross matching — cross′ match ing n. med the testing for compatibility of a donor s and a recipient s blood prior to transfusion, in which serum of each is mixed with red blood cells of the other and observed for hemagglutination …   From formal English to slang

  • cross matching — noun Etymology: cross (III) : the testing of the compatibility of the bloods of transfusion donor and recipient by mixing the serum of each with the red cells of the other to determine the absence of agglutinative reactions * * * Med. the testing …   Useful english dictionary

  • cross matching — Med. the testing for compatibility of a donor s and a recipient s blood prior to transfusion, in which serum of each is mixed with red blood cells of the other and observed for hemagglutination. Also, crossmatch /kraws mach , kros /. [1935 40] *… …   Universalium

  • cross matching — crossmatching …   Medical dictionary

  • cross-match — /kraws mach , kros /, v.t. 1. to match (related items from two or more lists or groups). 2. Med. to subject (blood) to cross matching. [1925 30] * * * crossˈ match transitive verb To test (blood samples from a donor and a recipient) for… …   Useful english dictionary

  • cross-match — /kraws mach , kros /, v.t. 1. to match (related items from two or more lists or groups). 2. Med. to subject (blood) to cross matching. [1925 30] * * * …   Universalium

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