cytochrome c oxidase


cytochrome c oxidase
A cytochrome of the a type, containing copper, that catalyzes the oxidation of 4ferrocytochrome c by molecular oxygen to 4ferricytochrome c and 2H2O. A part of Complex IV of the respiratory chain. A deficiency of one or more of the polypeptides of this complex results in neuronal loss in brain leading to psychomotor retardation and neurodegenerative disease. SYN: cytochrome aa3, indophenol oxidase, indophenolase.

Medical dictionary. 2011.

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