Cox-1 (cyclooxygenase-1)
This protein acts as an enzyme and specifically catalyzes (speeds) the production of certain chemical messengers (called prostaglandins). The prostaglandins work within certain cells responsible for inflammation and other functions. In the stomach, for example, they promote the production of the natural mucus lining which protects the inner stomach. Because the common antiinflammatory drugs (like aspirin, ibuprofen and naproxen) block the action of Cox-1, they can reduce inflammation, but they can also decrease the natural stomach protective mucus lining and lead to stomach upset, intestinal bleeding, and ulcers.

Medical dictionary. 2011.

Look at other dictionaries:

  • Cyclooxygenase-1 — Vorhandene Strukturdaten …   Deutsch Wikipedia

  • cyclooxygenase-1 — noun an enzyme that regulates prostaglandins that are important for the health of the stomach lining and kidneys an unfortunate side effect of NSAIDs is that they block Cox 1 • Syn: ↑Cox 1 • Hypernyms: ↑cyclooxygenase, ↑Cox …   Useful english dictionary

  • COX-1 — Cyclooxygenase 1 Oberflächenmodell nach PDB  …   Deutsch Wikipedia

  • Cyclooxygenase 2 — Kalottenmodell der COX 2 nach PDB  …   Deutsch Wikipedia

  • COX-2 — Cyclooxygenase 2 Kalottenmodell der COX 2 nach PDB  …   Deutsch Wikipedia

  • Cyclooxygenase — Cyclooxygenasen Kalottenmodell der Cyclooxygenase 2 mit dem Inhibitor Indometa …   Deutsch Wikipedia

  • COX-2-Inhibitor — Als COX 2 Hemmer oder auch COX 2 Inhibitor bezeichnet man eine Gruppe von entzündungshemmenden Arzneistoffen, bei der nur eine der Unterformen der Cyclooxygenase (COX) gehemmt wird. Die wichtigsten Unterformen dieses Enzyms sind die… …   Deutsch Wikipedia

  • Cyclooxygenase-2 — Vorhandene Strukturdaten: PDB  …   Deutsch Wikipedia

  • Cyclooxygenase — COX redirects here. For other meanings, see Cox (disambiguation). prostaglandin endoperoxide synthase Identifiers EC number CAS number …   Wikipedia

  • Cox-2 inhibitor — A class of drugs that selectively blocks a specific enzyme called Cox 2. Blocking this enzyme impedes the production of the chemical messengers that cause the pain and swelling of arthritis inflammation. Cyclooxygenase 1 (Cox 1) is an enzyme… …   Medical dictionary

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