dehydrogenase


dehydrogenase
Class name for those enzymes that oxidize substrates by catalyzing removal of hydrogen from metabolites (hydrogen donors) and transferring it to other substances (hydrogen acceptors), which are thus reduced; most of the oxidative enzymes (oxidoreductases, EC class 1) perform their oxidations in this manner.
- aerobic d. an enzyme (usually a metalloflavoenzyme) catalyzing the transfer of hydrogen from some metabolite to oxygen, forming hydrogen peroxide in the process; e.g., xanthine oxidase and others in several sub-subclasses ( e.g., EC 1.1.3, 1.2.3, 1.7.3, 1.8.3, 1.10.3).
- anaerobic d. an enzyme (usually a pyridinoenzyme) catalyzing the transfer of hydrogen from some metabolite to some acceptor molecule ( e.g., NAD+, cytochrome) other than oxygen; e.g., lactate dehydrogenases, isocitrate dehydrogenases, and others in EC class 1, excluding those listed under aerobic d..
- α-keto acid d. See α-keto acid d..
- Robison ester d. SYN: glucose-6-phosphate d..

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de·hy·dro·ge·nase .dē-(.)hī-'dräj-ə-.nās, (')dē-'hī-drə-jə-, -.nāz n an enzyme that accelerates the removal of hydrogen from metabolites and its transfer to other substances see SUCCINATE DEHYDROGENASE

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n.

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de·hy·dro·gen·ase (de-hiґdro-jən″ās) an enzyme of the oxidoreductase class [EC 1] that catalyzes the transfer of hydrogen or electrons from a donor, which becomes oxidized, to an acceptor compound, which becomes reduced. Dehydrogenases are usually designated according to the hydrogen donor.

Medical dictionary. 2011.

Look at other dictionaries:

  • dehydrogenase — ☆ dehydrogenase [dē hī′drə jən ās΄, dē΄hī drä′jə nās΄ ] n. [ DE + HYDROGEN + ASE] any oxidoreductase enzyme that acts as a catalyst, in chemical reactions involving oxidation, by the removal of hydrogen …   English World dictionary

  • Dehydrogenase — A dehydrogenase (also called DHO in the literature) is an enzyme that oxidises a substrate by a reduction reaction that transfers one or more hydrides (H−) to an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN.… …   Wikipedia

  • Dehydrogenase — Eine Dehydrogenase ist ein Enzym, das sein Substrat durch Abspaltung von Wasserstoffatomen oxidiert. Dehydrogenasen gehören zur Gruppe I (Oxidoreduktasen) der EC Klassifikation. Der abgespaltene Wasserstoff wird auf Cosubstrate wie NAD+ oder FAD… …   Deutsch Wikipedia

  • dehydrogenase — noun Etymology: International Scientific Vocabulary Date: 1923 an enzyme that accelerates the removal of hydrogen from metabolites and its transfer to other substances compare succinate dehydrogenase …   New Collegiate Dictionary

  • Dehydrogenase — De|hy|d|ro|ge|na|se [↑ de u. ↑ Hydrogenase], die; , n: veraltetes Syn.: Dehydrase: ein Enzym (↑ Oxidoreduktase), das die Ablösung von 2 Wasserstoff Atomen aus org. Verb. (↑ Oxidation) u. anschließend (als Hydrogenase) die Übertragung von H2 auf… …   Universal-Lexikon

  • dehydrogenase — dehidrogenazė statusas T sritis chemija apibrėžtis Fermentas, katalizuojantis dviejų vandenilio atomų atskilimą nuo substrato. atitikmenys: angl. dehydrogenase rus. дегидрогеназа …   Chemijos terminų aiškinamasis žodynas

  • dehydrogenase — (|)dē+ noun Etymology: International Scientific Vocabulary de + hydrogenase : any of various enzymes that accelerate the removal of hydrogen from metabolites and its transfer to other substances (as diphosphopyridine nucleotide) and thus play an… …   Useful english dictionary

  • dehydrogenase — Enzyme that oxidizes a substrate by transferring hydrogen to an acceptor that is either NAD+/NADP+ or a flavin enzyme …   Dictionary of molecular biology

  • dehydrogenase — /dee huy dreuh jeuh nays , nayz /, n. Biochem. an oxidoreductase enzyme that catalyzes the removal of hydrogen. [1920 25; DEHYDROGEN(ATE) + ASE] * * * …   Universalium

  • dehydrogenase — noun Any of several enzymes that catalyze the removal of hydrogen (a proton) from biological compounds …   Wiktionary


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