endopeptidase

endopeptidase
An enzyme catalyzing the hydrolysis of a peptide chain at points well within the chain, not near termini; e.g., pepsin, trypsin. Cf.:exopeptidase. SYN: proteinase.

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en·do·pep·ti·dase -'pep-tə-.dās, -.dāz n any of a group of enzymes that hydrolyze peptide bonds inside the long chains of protein molecules: PROTEASE compare EXOPEPTIDASE

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n.
a digestive enzyme (e.g. pepsin) that splits a whole protein into small peptide fractions by splitting the linkages between peptides in the interior of the molecule. Compare exopeptidase. See also peptidase.

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en·do·pep·ti·dase (en″do-pepґtĭ-dās) [EC 3.4.21–99] any peptidase that catalyzes the cleavage of internal peptide bonds in a polypeptide or protein; they are divided into subclasses on the basis of catalytic mechanism and comprise the serine endopeptidases, cysteine endopeptidases, aspartic endopeptidases, metalloendopeptidases, and other endopeptidases.

Medical dictionary. 2011.

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  • endopeptidase — [en΄dōpep′tə dās΄] n. any enzyme, as pepsin, that starts to hydrolyze peptide bonds in the interior of a peptide chain …   English World dictionary

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  • endopeptidase — noun Date: 1936 any of a group of enzymes that hydrolyze peptide bonds within the long chains of protein molecules ; protease compare exopeptidase …   New Collegiate Dictionary

  • Endopeptidase — Endopeptidasen gehören wie die Exopeptidasen zu den Peptidasen. Endopeptidasen spalten enzymatisch Peptidbindungen innerhalb des Proteins. Sie sind meist sehr spezifisch für bestimmte Aminosäuren. Beispiele sind: Pepsin Trypsin: spezifisch für… …   Deutsch Wikipedia

  • Endopeptidase — Peptidase Coupure protéolytique d une chaîne peptidique Les peptidases (ou protéases ou enzymes protéolytiques) sont des enzymes qui brisent les liaisons peptidiques des protéines. On parle alors de coupure protéolytique ou de protéolyse. Ce… …   Wikipédia en Français

  • endopeptidase — An enzyme that cleaves protein at positions within the chain. Formally, the enzymes are peptidyl peptide hydrolases, more usually known as proteinases or proteolytic enzymes …   Dictionary of molecular biology

  • endopeptidase — /en doh pep ti days , dayz /, n. Biochem. an enzyme that catalyzes the cleavage of a polypeptide or protein at interior positions of the amino acid chain. [1935 40; ENDO + PEPTIDASE] * * * …   Universalium

  • endopeptidase — noun Any of a group of enzymes, such as trypsin, chymotrypsin, pepsin and elastase, which catalyze the splitting of polypeptide chains …   Wiktionary

  • Endopeptidase — Ẹn|do|pep|ti|da|se [↑ endo (1) u. ↑ Peptidase] svw. ↑ Proteinase …   Universal-Lexikon

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