fibrillin

fibrillin
A microfibrillar protein in connective tissue with a wide distribution in the body; molecular weight about 350,000. There is good evidence that Marfan syndrome is due to mutations of f. [MIM*134797]. [Mod. L. fibrilla, fibril, + -in]

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fi·bril·lin 'fī-brə-lin, 'fib-rə- n a large extracellular glycoprotein of connective tissue that is a structural component of microfibrils associated esp. with elastin

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fi·bril·lin (fi-brilґin) a glycoprotein that is the main component of extracellular microfibrils and, with elastin, forms elastic fibers; in humans, there are two forms, designated fibrillin 1 and fibrillin 2. Abnormal fibrillin metabolism results in a variety of connective tissue disorders.

Medical dictionary. 2011.

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  • fibrillin — fibrillin. См. фибриллин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Fibrillin — protein Name= fibrillin 1 caption= width= HGNCid=3603 Symbol=FBN1 AltSymbols=FBN, MFS1, WMS EntrezGene=2200 OMIM=134797 RefSeq=NM 000138 UniProt=P35555 PDB= ECnumber= Chromosome=15 Arm=q Band=21.1 LocusSupplementaryData=protein Name=fibrillin 2… …   Wikipedia

  • fibrillin — Widely distributed connective tissue protein (350 kD) associated with microfibrils (10nm diameter) …   Dictionary of molecular biology

  • fibrillin — noun A glycoprotein present in human skin, necessary for forming the elastic fibres in connective tissue …   Wiktionary

  • Fibrillin — Fi|bril|lin, das; (Med.): Hauptbestandteil der Fibrillen …   Universal-Lexikon

  • Fibrillin — Fi|brilli̱n: Hauptbestandteil der Fibrillen …   Das Wörterbuch medizinischer Fachausdrücke

  • fibrillin — fiˈbrillin noun A protein found in connective tissue • • • Main Entry: ↑fibril …   Useful english dictionary

  • FBN1 — Fibrillin 1 PDB rendering based on 1apj …   Wikipedia

  • фибриллин — fibrillin фибриллин (см. Marfan syndrome). (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Marfan syndrome — Marfan redirects here. For the person after whom the syndrome is named, see Antoine Marfan. Marfan syndrome Classification and external resources Micrograph demonstrating myxomatous degeneration of the aorti …   Wikipedia

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