glycerol-3-phosphate dehydrogenase


glycerol-3-phosphate dehydrogenase
α-Glycerol phosphate dehydrogenase; 3-phosphoglycerol dehydrogenase; a flavoenzyme that catalyzes the interconversion of dihydroxyacetone phosphate and sn-glycerol 3-phosphate, with the participation of NAD+; its action provides the glycerol moiety from carbohydrate during lipogenesis.

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glyc·er·ol-3-phos·phate de·hy·dro·gen·ase (glisґər-ol fosґfāt de-hiґdro-jə-nās) [EC 1.1.99.5] an enzyme of the oxidoreductase class that catalyzes the oxidation of glycerol 3-phosphate to dihydroxyacetone phosphate. In mitochondria of striated muscle and of nervous tissue, the enzyme contains iron and the acceptor is FAD. The dihydroxyacetone phosphate formed can cross into the cytosol, where glycerol-3-phosphate dehydrogenase (NAD+) catalyzes its reduction via electrons from NADH, regenerating glycerol 3-phosphate. See also glycerol phosphate shuttle, under shuttle.

Medical dictionary. 2011.

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  • Glycerol-3-phosphate dehydrogenase — protein Name=glycerol 3 phosphate dehydrogenase 1 (soluble) caption= width= HGNCid=4455 Symbol=GPD1 AltSymbols= EntrezGene=2819 OMIM=138420 RefSeq=NM 005276 UniProt=P21695 PDB= ECnumber=1.1.1.8 Chromosome=12 Arm=q Band=12 LocusSupplementaryData=… …   Wikipedia

  • Glycerol-3-phosphate dehydrogenase (NAD+) — In enzymology, a glycerol 3 phosphate dehydrogenase (NAD+) (EC number|1.1.1.8) is an enzyme that catalyzes the chemical reaction:sn glycerol 3 phosphate + NAD+ ightleftharpoons glycerone phosphate + NADH + H+Thus, the two substrates of this… …   Wikipedia

  • Glycerol-3-phosphate dehydrogenase (NAD(P)+) — In enzymology, a glycerol 3 phosphate dehydrogenase [NAD(P)+] (EC number|1.1.1.94) is an enzyme that catalyzes the chemical reaction:sn glycerol 3 phosphate + NAD(P)+ ightleftharpoons glycerone phosphate + NAD(P)H + H+The 3 substrates of this… …   Wikipedia

  • Glycerol-1-phosphate dehydrogenase (NAD(P)+) — In enzymology, a glycerol 1 phosphate dehydrogenase [NAD(P)+] (EC number|1.1.1.261) is an enzyme that catalyzes the chemical reaction:sn glycerol 1 phosphate + NAD(P)+ ightleftharpoons glycerone phosphate + NAD(P)H + H+The 3 substrates of this… …   Wikipedia

  • glycerol-3-phosphate dehydrogenase (NAD+) — glyc·er·ol 3 phos·phate de·hy·dro·gen·ase (NAD+) (glisґər ol fosґfāt de hiґdro jən ās) [EC 1.1.1.8] a cytosolic enzyme of the oxidoreductase class that catalyzes the oxidation of glycerol 3 phosphate to dihydroxyacetone… …   Medical dictionary

  • Glycerol 3-phosphate — Chembox new ImageFile = glycerol 3 phosphate.png ImageSize = 150px IUPACName = 1,2,3 Propanetriol, 1 (dihydrogen phosphate) OtherNames = Glycerol 1 phosphate Glycerophosphate α glycerolphosphate Section1 = Chembox Identifiers CASNo = 57 03 4… …   Wikipedia

  • Glycerol-3-phosphate 1-dehydrogenase (NADP+) — In enzymology, a glycerol 3 phosphate 1 dehydrogenase (NADP+) (EC number|1.1.1.177) is an enzyme that catalyzes the chemical reaction:sn glycerol 3 phosphate + NADP+ ightleftharpoons D glyceraldehyde 3 phosphate + NADPH + H+Thus, the two… …   Wikipedia

  • Glycerol — Glycerine and Glycerin redirect here. For the Bush song, see Glycerine (song). Glycerol …   Wikipedia

  • Glycerol phosphate shuttle — The glycerol 3 phosphate shuttle is a mechanism that regenerates NAD+ from NADH, a by product of glycolysis. Its importance in transporting reducing equivalents is secondary to the malate aspartate shuttle.ReactionIn this shuttle, the enzyme… …   Wikipedia

  • Glycerol 2-dehydrogenase (NADP+) — In enzymology, a glycerol 2 dehydrogenase (NADP+) (EC number|1.1.1.156) is an enzyme that catalyzes the chemical reaction:glycerol + NADP+ ightleftharpoons glycerone + NADPH + H+Thus, the two substrates of this enzyme are glycerol and NADP+,… …   Wikipedia


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