- A metabolic disorder in which serum concentration of pipecolic acid is greatly increased; characterized by hepatomegaly and progressive, generalized demyelination of the nervous system. SYN: hyperpipecolic acidemia.
* * *hy·per·pip·e·co·la·te·mia (hi″pər-pip″ə-kol″ə-teґme-ə) excess of pipecolic acid in the blood, usually associated with cerebrohepatorenal syndrome but also a consequence of hyperlysinemia.
Medical dictionary. 2011.