6-Oxypurine; purin-6(1H)-one; a purine present in the muscles and other tissues, formed during purine catabolism by deamination of adenine; elevated in molybdenum-cofactor deficiency. SYN: 6-hydroxypurine.
- h. phosphoribosyltransferase an enzyme present in human tissue that converts h. and guanine to their respective 5′ nucleotides, with 5-phosphoribose 1-diphosphate as the ribose-phosphate donor; a partial deficiency of this enzyme can result in elevated purine biosynthesis resulting in gout; another level of deficiency is associated with Lesch-Nyhan syndrome. SYN: h. guanine phosphoribosyltransferase.

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hy·po·xan·thine .hī-pō-'zan-.thēn n a purine base C5H4N4O found in plant and animal tissues that yields xanthine on oxidation and is an intermediate in uric acid synthesis

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hy·po·xan·thine (hi″po-zanґthēn) 6-oxypurine, a purine base formed as an intermediate in the degradation of purines and purine nucleosides to uric acid and in the salvage of free purines. It is found in some transfer RNA molecules and occurs complexed with ribose as the nucleoside inosine.

Medical dictionary. 2011.

Look at other dictionaries:

  • Hypoxanthine — Général No CAS …   Wikipédia en Français

  • hypoxanthine — hypoxanthine. См. 6 оксипурин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • hypoxanthine — [hī΄pōzan′thēn΄, hī΄pəzan′thēn΄, hī΄pō zan′thin, hī΄pə zan′thin] n. a nitrogenous compound, C5H4N4O, formed in the body from the breakdown of nucleic acids …   English World dictionary

  • Hypoxanthine — Chembox new ImageFile=Hypoxanthin Hypoxanthine.svg ImageSize= IUPACName=3,7 dihydropurin 6 one OtherNames= Section1= Chembox Identifiers CASNo=68 94 0 PubChem=790 SMILES=O=C1NC=Nc2nc [nH] c12 MeSHName=Hypoxanthine Section2= Chembox Properties… …   Wikipedia

  • hypoxanthine — hipoksantinas statusas T sritis chemija formulė HOC₅H₃N₄ santrumpa( os) Hyp atitikmenys: angl. hypoxanthine rus. гипоксантин ryšiai: sinonimas – 6 purinolis …   Chemijos terminų aiškinamasis žodynas

  • hypoxanthine — noun Etymology: International Scientific Vocabulary Date: circa 1857 a purine base C5H4N4O found in plant and animal tissues that yields xanthine on oxidation …   New Collegiate Dictionary

  • hypoxanthine — a chemical formed in fish muscle after death; can be used as a measure of the freshness of the fish …   Dictionary of ichthyology

  • hypoxanthine — Purine base present in inosine monophosphate (IMP) from which adenosine monophosphate (AMP) and guanosine monophosphate (GMP) are made. The product of deamination of adenine, 6 hydroxy purine …   Dictionary of molecular biology

  • hypoxanthine — hypoxanthic, adj. /huy peuh zan theen, thin/, n. a white, crystalline, almost water soluble, alkaloidal purine derivative, C5H4N4O, found in animal and vegetable tissues: used chiefly in biochemical research. [1835 45; HYPO + XANTHINE] * * * …   Universalium

  • hypoxanthine — noun A bicyclic heterocycle 3,7 dihydropurin 6 one that is an intermediate in the biosynthesis of uric acid …   Wiktionary