imidazole

imidazole
A five-membered heterocyclic compound occurring in l-histidine and other biologically important compounds.
- i. alkaloids alkaloids containing one or more i. moieties as part of its structure ( E.G., pilocarpine).

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im·id·az·ole .im-ə-'daz-.ōl n
1) a white crystalline heterocyclic base C3H4N2 that is an antimetabolite related to histidine
2) any of a large class of derivatives of imidazole including histidine and histamine

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n.
one of a group of chemically related antifungal drugs that are also effective against a wide range of bacteria; some (e.g. tiabendazole and mebendazole) are also used as anthelmintics. The group includes econazole, clotrimazole, ketoconazole, and miconazole. They are administered by mouth or externally as creams.

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im·id·az·ole (im″id-azґōl) 1. a five-membered heterocyclic organic compound containing two nitrogen atoms in the ring: It is a type of azole, and is an antimetabolite and inhibitor of histamine and is used as an insecticide. 2. any of a class of fungistatic compounds containing such a ring, a subset of the class of azole antifungals, effective against a wide range of fungi; they alter cell membrane functions and permeability by inhibiting the biosynthesis of ergosterol.


Medical dictionary. 2011.

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  • Imidazole — Strukturformel von Imidazol Imidazole sind ein chemische Stoffgruppe aus dem Bereich der heterocyclischen Verbindungen und gehören zur Gruppe der Azole. Ihre Mitglieder sind fünfgliedrige cyclische organische ungesättigte Verbindungen, die genau… …   Deutsch Wikipedia

  • imidazole — /im id az ohl, id euh zohl /, n. Chem. a colorless, crystalline, water soluble, heterocyclic compound, C3H4N2, used chiefly in organic synthesis. Also called glyoxaline. [1890 95; IMIDE + AZOLE] * * * ▪ organic compound class       any of a class …   Universalium

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  • Imidazole N-acetyltransferase — In enzymology, an imidazole N acetyltransferase (EC number|2.3.1.2) is an enzyme that catalyzes the chemical reaction:acetyl CoA + imidazole ightleftharpoons CoA + N acetylimidazoleThus, the two substrates of this enzyme are acetyl CoA and… …   Wikipedia

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