isocitrate

isocitrate
- i. dehydrogenase one of two enzymes that catalyze the conversion of threo-ds-i., the product of the action of both aconitase and i. lyase, to α-ketoglutarate (2-oxoglutarate) and CO2; one of the isozymes uses NAD+ (participating in the tricarboxylic acid cycle), while the other uses NADP+. SYN: isocitric acid dehydrogenase, oxalosuccinic carboxylase.
- i. lyase an enzyme that catalyzes the reversible aldol condensation of glyoxylate and succinate, forming threo-ds-i.; participates in the glyoxylate cycle. SYN: isocitrase, isocitratase, isocitritase.

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iso·cit·rate .ī-sō-'si-.trāt n any salt or ester of isocitric acid also ISOCITRIC ACID

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iso·ci·trate (i″so-sĭґtrāt) a fully dissociated (ionized) salt of isocitric acid.

Medical dictionary. 2011.

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